STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CD109CD109 antigen isoform 1 preproprotein. (1449 aa)    
Predicted Functional Partners:
ALPL
Alkaline phosphatase.
     
 0.615
CD248
CD248 molecule.
      
 0.611
CD9
CD9 antigen; Integral membrane protein associated with integrins, which regulates different processes, such as sperm-egg fusion, platelet activation and aggregation, and cell adhesion (By similarity). Present at the cell surface of oocytes and plays a key role in sperm-egg fusion, possibly by organizing multiprotein complexes and the morphology of the membrane required for the fusion (By similarity). In myoblasts, associates with CD81 and PTGFRN and inhibits myotube fusion during muscle regeneration (By similarity). In macrophages, associates with CD81 and beta-1 and beta-2 integrins, [...]
     
 0.596
PRSS12
Serine protease 12; Belongs to the peptidase S1 family.
    
 
 0.564
TMPRSS6
Transmembrane serine protease 6; Belongs to the peptidase S1 family.
    
 
 0.563
TMPRSS3
Transmembrane serine protease 3; Belongs to the peptidase S1 family.
    
 
 0.535
SLC4A10
Anion exchange protein.
      
 0.533
SLC4A7
Anion exchange protein.
      
 0.528
EMP1
Epithelial membrane protein 1.
   
  
 0.524
AMIGO2
Adhesion molecule with Ig like domain 2.
      
 0.514
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.