CCL5 protein (Sus scrofa) - STRING interaction network

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CCL5

C-C motif chemokine 5; Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. May also be an agonist of the G protein-coupled receptor GPR75. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells. Belongs to the intercrine beta (chemokine CC) family. (91 aa)

Predicted Functional Partners:

CCR5

0.997

CCR1

0.996

CCL17

0.996

CCR2

0.995

CXCL10

0.994

CCL28

0.993

CCL24

0.993

CCL26

0.992

CCR4

0.990

CXCL9

0.989

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCL17	CCL24	ENSSSCP00000020489	ENSSSCP00000032478	C-C motif chemokine.	SCY domain-containing protein.	0.727
CCL17	CCL26	ENSSSCP00000020489	ENSSSCP00000057456	C-C motif chemokine.	C-C motif chemokine.	0.961
CCL17	CCL28	ENSSSCP00000020489	ENSSSCP00000017879	C-C motif chemokine.	C-C motif chemokine.	0.945
CCL17	CCL5	ENSSSCP00000020489	ENSSSCP00000028561	C-C motif chemokine.	C-C motif chemokine 5; Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. May also be an agonist of the G protein-coupled receptor GPR75. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells. Belongs to the intercrine beta (chemokine CC) family.	0.996
CCL17	CCR1	ENSSSCP00000020489	ENSSSCP00000012073	C-C motif chemokine.	Chemokine (C-C motif) receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.946
CCL17	CCR2	ENSSSCP00000020489	ENSSSCP00000024949	C-C motif chemokine.	C-C chemokine receptor type 2 isoform B; Belongs to the G-protein coupled receptor 1 family.	0.937
CCL17	CCR4	ENSSSCP00000020489	ENSSSCP00000033921	C-C motif chemokine.	C-C chemokine receptor type 4 isoform X1; Belongs to the G-protein coupled receptor 1 family.	0.974
CCL17	CCR5	ENSSSCP00000020489	ENSSSCP00000072998	C-C motif chemokine.	C-C motif chemokine receptor 5 (gene/pseudogene); Belongs to the G-protein coupled receptor 1 family.	0.840
CCL17	CXCL10	ENSSSCP00000020489	ENSSSCP00000032297	C-C motif chemokine.	C-X-C motif chemokine.	0.686
CCL17	CXCL9	ENSSSCP00000020489	ENSSSCP00000046312	C-C motif chemokine.	C-X-C motif chemokine.	0.677
CCL24	CCL17	ENSSSCP00000032478	ENSSSCP00000020489	SCY domain-containing protein.	C-C motif chemokine.	0.727
CCL24	CCL26	ENSSSCP00000032478	ENSSSCP00000057456	SCY domain-containing protein.	C-C motif chemokine.	0.968
CCL24	CCL28	ENSSSCP00000032478	ENSSSCP00000017879	SCY domain-containing protein.	C-C motif chemokine.	0.945
CCL24	CCL5	ENSSSCP00000032478	ENSSSCP00000028561	SCY domain-containing protein.	C-C motif chemokine 5; Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. May also be an agonist of the G protein-coupled receptor GPR75. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells. Belongs to the intercrine beta (chemokine CC) family.	0.993
CCL24	CCR1	ENSSSCP00000032478	ENSSSCP00000012073	SCY domain-containing protein.	Chemokine (C-C motif) receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.939
CCL24	CCR2	ENSSSCP00000032478	ENSSSCP00000024949	SCY domain-containing protein.	C-C chemokine receptor type 2 isoform B; Belongs to the G-protein coupled receptor 1 family.	0.930
CCL24	CCR4	ENSSSCP00000032478	ENSSSCP00000033921	SCY domain-containing protein.	C-C chemokine receptor type 4 isoform X1; Belongs to the G-protein coupled receptor 1 family.	0.879
CCL24	CCR5	ENSSSCP00000032478	ENSSSCP00000072998	SCY domain-containing protein.	C-C motif chemokine receptor 5 (gene/pseudogene); Belongs to the G-protein coupled receptor 1 family.	0.914
CCL24	CXCL10	ENSSSCP00000032478	ENSSSCP00000032297	SCY domain-containing protein.	C-X-C motif chemokine.	0.570
CCL24	CXCL9	ENSSSCP00000032478	ENSSSCP00000046312	SCY domain-containing protein.	C-X-C motif chemokine.	0.553

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