STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PCK1Phosphoenolpyruvate carboxykinase 1. (841 aa)    
Predicted Functional Partners:
ENO2
Enolase 2.
     
 0.981
CS
Citrate synthase, mitochondrial; Belongs to the citrate synthase family.
   
 
 0.968
ENO4
Enolase 4.
     
 0.957
PKLR
Pyruvate kinase; Belongs to the pyruvate kinase family.
   
 
 0.954
ENO3
Beta-enolase; Appears to have a function in striated muscle development and regeneration; Belongs to the enolase family.
     
 0.953
ENO1
Alpha-enolase isoform X1.
     
 0.946
ACLY
ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.
   
 
 0.942
MDH1
Malate dehydrogenase, cytoplasmic.
   
 
 0.941
MDH2
Malate dehydrogenase, mitochondrial.
   
 
 0.936
PKM
Multifunctional fusion protein; Belongs to the pyruvate kinase family.
   
 
 0.920
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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