STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
GYPAGlycophorin-A; Glycophorin A is the major intrinsic membrane sialoglycoprotein of the erythrocyte. Appears to be important for the function of SLC4A1 and is required for high activity of SLC4A1. May be involved in translocation of SLC4A1 to the plasma membrane (By similarity). (164 aa)    
Predicted Functional Partners:
AQP1
Aquaporin-1; Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.
   
 0.945
RHAG
Rh associated glycoprotein; Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
   
 0.886
KEL
Kell metallo-endopeptidase (Kell blood group).
   
  
 0.753
RHCE
Rh protein; Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
   
 
 0.732
SLC4A1
Anion exchange protein.
   
 0.721
TRIM10
Tripartite motif-containing protein 10; Seems to play an important role in erythropoiesis.
   
  
 0.690
EPB42
Erythrocyte membrane protein band 4.2.
   
 0.683
CD34
CD34 molecule.
      
 0.668
GYPC
Uncharacterized protein.
      
 0.647
OSGEP
Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.
      
 0.626
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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