Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CSNK2BCasein kinase II subunit beta; Participates in Wnt signaling. Plays a complex role in regulating the basal catalytic activity of the alpha subunit (By similarity). (298 aa)    
Predicted Functional Partners:
CSNK2A2
Casein kinase 2, alpha prime polypeptide; Belongs to the protein kinase superfamily.
   
 0.994
CSNK2A1
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 0.994
RNF2
Ring finger protein 2.
    
 0.975
RING1
Ring finger protein 1.
    
 0.960
NFKBIA
NF-kappa-B inhibitor alpha; Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.
    
  0.940
DVL1
Dishevelled segment polarity protein 1.
    
 0.926
PCGF5
Polycomb group RING finger protein 5 isoform X1.
    
 0.920
FUNDC1
FUN14 domain containing 1.
   
 
 0.919
PCGF3
Polycomb group ring finger 3.
    
 0.914
CTNNB1
Catenin beta 1.
   
 0.906
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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