STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RTF2Replication termination factor 2; Replication termination factor which is a component of the elongating replisome. Required for ATR pathway signaling upon DNA damage and has a positive activity during DNA replication. Might function to facilitate fork pausing at replication fork barriers like the rDNA. May be globally required to stimulate ATR signaling after the fork stalls or encounters a lesion. Interacts with nascent DNA. Belongs to the rtf2 family. (305 aa)    
Predicted Functional Partners:
RTF1
RTF1 homolog, Paf1/RNA polymerase II complex component.
   
  
 0.770
HOXB8
Homeobox protein Hox-B8; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis; Belongs to the Antp homeobox family.
      
 0.574
KCTD19
Potassium channel tetramerization domain containing 19.
      
 0.552
SCML2
Scm polycomb group protein like 2.
      
 0.546
ELMSAN1
ELM2 and Myb/SANT domain containing 1.
      
 0.525
SDE2
SDE2 telomere maintenance homolog.
      
 0.517
MEIKIN
Meiotic kinetochore factor.
      
 0.508
TRERF1
Transcriptional regulating factor 1.
      
 0.506
RBM17
RNA binding motif protein 17.
      
 0.502
RPS11
Ribosomal protein S11; Belongs to the universal ribosomal protein uS17 family.
      
 0.495
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.