PAK1 protein (Sus scrofa) - STRING interaction network

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Known Interactions

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Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

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[Homology]

Score

PAK1

Non-specific serine/threonine protein kinase. (546 aa)

Predicted Functional Partners:

CDC42

0.997

RAC3

0.969

NCK1

0.964

ARHGEF6

0.960

RAC2

0.960

ARHGEF7

0.956

NCK2

0.953

TIAM1

0.950

RHOA

0.949

LIMK2

0.930

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGEF6	ARHGEF7	ENSSSCP00000043202	ENSSSCP00000033427	Rac/Cdc42 guanine nucleotide exchange factor 6.	Rho guanine nucleotide exchange factor 7.	0.926
ARHGEF6	CDC42	ENSSSCP00000043202	ENSSSCP00000029815	Rac/Cdc42 guanine nucleotide exchange factor 6.	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	0.783
ARHGEF6	NCK1	ENSSSCP00000043202	ENSSSCP00000025894	Rac/Cdc42 guanine nucleotide exchange factor 6.	Cytoplasmic protein.	0.612
ARHGEF6	NCK2	ENSSSCP00000043202	ENSSSCP00000042553	Rac/Cdc42 guanine nucleotide exchange factor 6.	Cytoplasmic protein.	0.635
ARHGEF6	PAK1	ENSSSCP00000043202	ENSSSCP00000030505	Rac/Cdc42 guanine nucleotide exchange factor 6.	Non-specific serine/threonine protein kinase.	0.960
ARHGEF6	RAC2	ENSSSCP00000043202	ENSSSCP00000070230	Rac/Cdc42 guanine nucleotide exchange factor 6.	Rac family small GTPase 2.	0.938
ARHGEF6	RAC3	ENSSSCP00000043202	ENSSSCP00000047362	Rac/Cdc42 guanine nucleotide exchange factor 6.	Rac family small GTPase 3.	0.938
ARHGEF6	RHOA	ENSSSCP00000043202	ENSSSCP00000045785	Rac/Cdc42 guanine nucleotide exchange factor 6.	Transforming protein RhoA isoform 1.	0.522
ARHGEF7	ARHGEF6	ENSSSCP00000033427	ENSSSCP00000043202	Rho guanine nucleotide exchange factor 7.	Rac/Cdc42 guanine nucleotide exchange factor 6.	0.926
ARHGEF7	CDC42	ENSSSCP00000033427	ENSSSCP00000029815	Rho guanine nucleotide exchange factor 7.	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	0.968
ARHGEF7	NCK1	ENSSSCP00000033427	ENSSSCP00000025894	Rho guanine nucleotide exchange factor 7.	Cytoplasmic protein.	0.612
ARHGEF7	NCK2	ENSSSCP00000033427	ENSSSCP00000042553	Rho guanine nucleotide exchange factor 7.	Cytoplasmic protein.	0.635
ARHGEF7	PAK1	ENSSSCP00000033427	ENSSSCP00000030505	Rho guanine nucleotide exchange factor 7.	Non-specific serine/threonine protein kinase.	0.956
ARHGEF7	RAC2	ENSSSCP00000033427	ENSSSCP00000070230	Rho guanine nucleotide exchange factor 7.	Rac family small GTPase 2.	0.938
ARHGEF7	RAC3	ENSSSCP00000033427	ENSSSCP00000047362	Rho guanine nucleotide exchange factor 7.	Rac family small GTPase 3.	0.939
ARHGEF7	RHOA	ENSSSCP00000033427	ENSSSCP00000045785	Rho guanine nucleotide exchange factor 7.	Transforming protein RhoA isoform 1.	0.595
CDC42	ARHGEF6	ENSSSCP00000029815	ENSSSCP00000043202	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	Rac/Cdc42 guanine nucleotide exchange factor 6.	0.783
CDC42	ARHGEF7	ENSSSCP00000029815	ENSSSCP00000033427	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	Rho guanine nucleotide exchange factor 7.	0.968
CDC42	LIMK2	ENSSSCP00000029815	ENSSSCP00000054029	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	LIM domain kinase 2.	0.499
CDC42	NCK1	ENSSSCP00000029815	ENSSSCP00000025894	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	Cytoplasmic protein.	0.725