STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTPRFProtein tyrosine phosphatase receptor type F. (1919 aa)    
Predicted Functional Partners:
INSR
Tyrosine-protein kinase receptor.
    
 0.935
CTNNB1
Catenin beta 1.
   
 0.925
LRRC4B
Leucine rich repeat containing 4B.
    
 0.920
PTPN1
Tyrosine-protein phosphatase non-receptor type.
   
0.916
PTPN11
Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.
   
0.915
IRS2
Insulin receptor substrate 2.
    
 0.910
IRS1
Insulin receptor substrate 1.
    
 0.908
IRS4
Insulin receptor substrate 4.
    
  0.906
PPFIA3
PTPRF interacting protein alpha 3.
    
 0.807
PPFIBP1
PPFIA binding protein 1.
     
 0.746
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.