Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CASP3 | CASP6 | ENSSSCP00000049424 | ENSSSCP00000068855 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). | Caspase 6; Belongs to the peptidase C14A family. | 0.631 |
| CASP3 | CASP7 | ENSSSCP00000049424 | ENSSSCP00000043126 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). | Caspase 7; Belongs to the peptidase C14A family. | 0.916 |
| CASP3 | CASP8 | ENSSSCP00000049424 | ENSSSCP00000026484 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). | Caspase-8 isoform X2; Belongs to the peptidase C14A family. | 0.986 |
| CASP3 | VIM | ENSSSCP00000049424 | ENSSSCP00000031624 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). | Vimentin; Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally. | 0.810 |
| CASP6 | CASP3 | ENSSSCP00000068855 | ENSSSCP00000049424 | Caspase 6; Belongs to the peptidase C14A family. | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). | 0.631 |
| CASP6 | CASP7 | ENSSSCP00000068855 | ENSSSCP00000043126 | Caspase 6; Belongs to the peptidase C14A family. | Caspase 7; Belongs to the peptidase C14A family. | 0.421 |
| CASP6 | CASP8 | ENSSSCP00000068855 | ENSSSCP00000026484 | Caspase 6; Belongs to the peptidase C14A family. | Caspase-8 isoform X2; Belongs to the peptidase C14A family. | 0.967 |
| CASP6 | VIM | ENSSSCP00000068855 | ENSSSCP00000031624 | Caspase 6; Belongs to the peptidase C14A family. | Vimentin; Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally. | 0.785 |
| CASP7 | CASP3 | ENSSSCP00000043126 | ENSSSCP00000049424 | Caspase 7; Belongs to the peptidase C14A family. | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). | 0.916 |
| CASP7 | CASP6 | ENSSSCP00000043126 | ENSSSCP00000068855 | Caspase 7; Belongs to the peptidase C14A family. | Caspase 6; Belongs to the peptidase C14A family. | 0.421 |
| CASP7 | CASP8 | ENSSSCP00000043126 | ENSSSCP00000026484 | Caspase 7; Belongs to the peptidase C14A family. | Caspase-8 isoform X2; Belongs to the peptidase C14A family. | 0.952 |
| CASP7 | VIM | ENSSSCP00000043126 | ENSSSCP00000031624 | Caspase 7; Belongs to the peptidase C14A family. | Vimentin; Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally. | 0.785 |
| CASP8 | CASP3 | ENSSSCP00000026484 | ENSSSCP00000049424 | Caspase-8 isoform X2; Belongs to the peptidase C14A family. | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). | 0.986 |
| CASP8 | CASP6 | ENSSSCP00000026484 | ENSSSCP00000068855 | Caspase-8 isoform X2; Belongs to the peptidase C14A family. | Caspase 6; Belongs to the peptidase C14A family. | 0.967 |
| CASP8 | CASP7 | ENSSSCP00000026484 | ENSSSCP00000043126 | Caspase-8 isoform X2; Belongs to the peptidase C14A family. | Caspase 7; Belongs to the peptidase C14A family. | 0.952 |
| CASP8 | VIM | ENSSSCP00000026484 | ENSSSCP00000031624 | Caspase-8 isoform X2; Belongs to the peptidase C14A family. | Vimentin; Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally. | 0.777 |
| DES | MYBPC2 | ENSSSCP00000059483 | ENSSSCP00000064562 | Desmin; Muscle-specific type III intermediate filament essential for proper muscular structure and function. Plays a crucial role in maintaining the structure of sarcomeres, inter-connecting the Z-disks and forming the myofibrils, linking them not only to the sarcolemmal cytoskeleton, but also to the nucleus and mitochondria, thus providing strength for the muscle fiber during activity. In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z-line structures. May act as a sarcomeric microtubule-ancho [...] | Myosin binding protein C, fast type. | 0.631 |
| DES | MYL4 | ENSSSCP00000059483 | ENSSSCP00000018340 | Desmin; Muscle-specific type III intermediate filament essential for proper muscular structure and function. Plays a crucial role in maintaining the structure of sarcomeres, inter-connecting the Z-disks and forming the myofibrils, linking them not only to the sarcolemmal cytoskeleton, but also to the nucleus and mitochondria, thus providing strength for the muscle fiber during activity. In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z-line structures. May act as a sarcomeric microtubule-ancho [...] | Myosin light chain 4; Regulatory light chain of myosin. Does not bind calcium. | 0.553 |
| DES | TCAP | ENSSSCP00000059483 | ENSSSCP00000041916 | Desmin; Muscle-specific type III intermediate filament essential for proper muscular structure and function. Plays a crucial role in maintaining the structure of sarcomeres, inter-connecting the Z-disks and forming the myofibrils, linking them not only to the sarcolemmal cytoskeleton, but also to the nucleus and mitochondria, thus providing strength for the muscle fiber during activity. In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z-line structures. May act as a sarcomeric microtubule-ancho [...] | Uncharacterized protein. | 0.817 |
| DES | TPM2 | ENSSSCP00000059483 | ENSSSCP00000041804 | Desmin; Muscle-specific type III intermediate filament essential for proper muscular structure and function. Plays a crucial role in maintaining the structure of sarcomeres, inter-connecting the Z-disks and forming the myofibrils, linking them not only to the sarcolemmal cytoskeleton, but also to the nucleus and mitochondria, thus providing strength for the muscle fiber during activity. In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z-line structures. May act as a sarcomeric microtubule-ancho [...] | Uncharacterized protein; Belongs to the tropomyosin family. | 0.703 |
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