STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PATJPATJ crumbs cell polarity complex component. (1936 aa)    
Predicted Functional Partners:
MPP5
MAGUK p55 subfamily member 5 isoform X1; Belongs to the MAGUK family.
    
 0.995
AMOT
Angiomotin isoform X1.
    
 0.978
AMOTL1
Angiomotin-like protein 1 isoform X1.
    
 0.962
AMOTL2
Angiomotin like 2.
   
 0.953
TJP3
Tight junction protein 3; Belongs to the MAGUK family.
   
0.948
PARD3
Par-3 family cell polarity regulator.
    
0.930
UBE3A
Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates.
     
 0.914
ARHGEF18
Rho guanine nucleotide exchange factor 18 isoform X3.
   
 0.911
PLCB4
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
   
   0.716
CRB2
Crumbs cell polarity complex component 2.
   
 
 0.695
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.