STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DUSP23Dual specificity protein phosphatase 23. (150 aa)    
Predicted Functional Partners:
WEE1
Wee1-like protein kinase.
   
 
 0.577
WEE2
Wee1-like protein kinase 2; Oocyte-specific protein tyrosine kinase that phosphorylates and inhibits CDK1 and acts as a key regulator of meiosis during both prophase I and metaphase II. Required to maintain meiotic arrest in oocytes during the germinal vesicle (GV) stage, a long period of quiescence at dictyate prophase I, by phosphorylating CDK1 at 'Tyr-15', leading to inhibit CDK1 activity and prevent meiotic reentry. Also required for metaphase II exit during egg activation by phosphorylating CDK1 at 'Tyr-15', to ensure exit from meiosis in oocytes and promote pronuclear formation.
   
 
 0.577
PKMYT1
Protein kinase, membrane associated tyrosine/threonine 1.
   
 
 0.577
STK38
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
   
 
 0.556
STK38L
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
   
 
 0.556
PLK3
Serine/threonine-protein kinase PLK.
   
 
 0.518
PLK5
Serine/threonine-protein kinase PLK.
   
 
 0.518
PLK2
Serine/threonine-protein kinase PLK.
   
 
 0.518
PLK1
Serine/threonine-protein kinase PLK.
   
 
 0.518
PLK4
Polo like kinase 4.
   
 
 0.518
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.