STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CLPPATP-dependent Clp protease proteolytic subunit. (273 aa)    
Predicted Functional Partners:
CLPX
ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial.
 0.999
CLPB
ClpB homolog, mitochondrial AAA ATPase chaperonin.
  
 
 0.996
LONP1
Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand- specific manner. May regulate mi [...]
  
 
 0.940
HSPE1
Uncharacterized protein; Belongs to the GroES chaperonin family.
 
 
 0.838
SPX
Spexin hormone.
      
 0.821
NDUFS8
NADH dehydrogenase ubiquinone iron-sulfur protein 8, mitochondrial.
   
 
 0.819
LONP2
Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1.
  
 
 0.813
MRPS11
Mitochondrial ribosomal protein S11; Belongs to the universal ribosomal protein uS11 family.
  
 
 0.772
NDUFS7
Uncharacterized protein.
   
 
 0.768
TUFM
Elongation factor Tu.
  
  
 0.763
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.