STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC110255205SH3 domain-containing protein. (355 aa)    
Predicted Functional Partners:
BRK1
BRICK1 subunit of SCAR/WAVE actin nucleating complex.
    
 
 0.748
NCKAP1
NCK associated protein 1.
   
 
 0.743
CYFIP2
Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.
   
 
 0.740
NCKAP1L
NCK associated protein 1 like.
   
 
 0.630
WASF3
Wiskott-Aldrich syndrome protein family member 3 isoform X1.
   
 
 0.620
LOC110255211
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
   
  
 0.612
LOC100621431
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
   
  
 0.612
INPP5D
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform X1.
   
  
 0.537
WASF2
Wiskott-Aldrich syndrome protein family member 2 isoform 2.
   
 
 0.524
TREM2
Ig-like domain-containing protein.
      
 0.524
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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