node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DAZL | DDX4 | ENSSSCP00000073353 | ENSSSCP00000063433 | Deleted in azoospermia-like protein. | Probable ATP-dependent RNA helicase DDX4; ATP-dependent RNA helicase required during spermatogenesis to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the secondary piRNAs metabolic process, the production of piRNAs in fetal male germ cells through a ping-pong amplification cycl [...] | 0.876 |
DAZL | GFRA1 | ENSSSCP00000073353 | ENSSSCP00000048866 | Deleted in azoospermia-like protein. | GDNF family receptor alpha 1. | 0.690 |
DAZL | KIT | ENSSSCP00000073353 | ENSSSCP00000066488 | Deleted in azoospermia-like protein. | Mast/stem cell growth factor receptor Kit; Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Phosphorylates PIK3R1, PLCG1, SH2B2/APS and CBL. Activates the AKT1 signaling pathway by phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase. Activat [...] | 0.520 |
DAZL | NANOS2 | ENSSSCP00000073353 | ENSSSCP00000003352 | Deleted in azoospermia-like protein. | Nanos C2HC-type zinc finger 2; Belongs to the nanos family. | 0.821 |
DAZL | STRA8 | ENSSSCP00000073353 | ENSSSCP00000017519 | Deleted in azoospermia-like protein. | Stimulated by retinoic acid 8. | 0.861 |
DAZL | SYCP3 | ENSSSCP00000073353 | ENSSSCP00000034487 | Deleted in azoospermia-like protein. | Synaptonemal complex protein 3. | 0.791 |
DAZL | ZBTB16 | ENSSSCP00000073353 | ENSSSCP00000034371 | Deleted in azoospermia-like protein. | Zinc finger and BTB domain containing 16. | 0.748 |
DDX4 | DAZL | ENSSSCP00000063433 | ENSSSCP00000073353 | Probable ATP-dependent RNA helicase DDX4; ATP-dependent RNA helicase required during spermatogenesis to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the secondary piRNAs metabolic process, the production of piRNAs in fetal male germ cells through a ping-pong amplification cycl [...] | Deleted in azoospermia-like protein. | 0.876 |
DDX4 | GFRA1 | ENSSSCP00000063433 | ENSSSCP00000048866 | Probable ATP-dependent RNA helicase DDX4; ATP-dependent RNA helicase required during spermatogenesis to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the secondary piRNAs metabolic process, the production of piRNAs in fetal male germ cells through a ping-pong amplification cycl [...] | GDNF family receptor alpha 1. | 0.603 |
DDX4 | KIT | ENSSSCP00000063433 | ENSSSCP00000066488 | Probable ATP-dependent RNA helicase DDX4; ATP-dependent RNA helicase required during spermatogenesis to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the secondary piRNAs metabolic process, the production of piRNAs in fetal male germ cells through a ping-pong amplification cycl [...] | Mast/stem cell growth factor receptor Kit; Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Phosphorylates PIK3R1, PLCG1, SH2B2/APS and CBL. Activates the AKT1 signaling pathway by phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase. Activat [...] | 0.703 |
DDX4 | NANOS2 | ENSSSCP00000063433 | ENSSSCP00000003352 | Probable ATP-dependent RNA helicase DDX4; ATP-dependent RNA helicase required during spermatogenesis to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the secondary piRNAs metabolic process, the production of piRNAs in fetal male germ cells through a ping-pong amplification cycl [...] | Nanos C2HC-type zinc finger 2; Belongs to the nanos family. | 0.650 |
DDX4 | STRA8 | ENSSSCP00000063433 | ENSSSCP00000017519 | Probable ATP-dependent RNA helicase DDX4; ATP-dependent RNA helicase required during spermatogenesis to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the secondary piRNAs metabolic process, the production of piRNAs in fetal male germ cells through a ping-pong amplification cycl [...] | Stimulated by retinoic acid 8. | 0.865 |
DDX4 | SYCP3 | ENSSSCP00000063433 | ENSSSCP00000034487 | Probable ATP-dependent RNA helicase DDX4; ATP-dependent RNA helicase required during spermatogenesis to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the secondary piRNAs metabolic process, the production of piRNAs in fetal male germ cells through a ping-pong amplification cycl [...] | Synaptonemal complex protein 3. | 0.870 |
DDX4 | ZBTB16 | ENSSSCP00000063433 | ENSSSCP00000034371 | Probable ATP-dependent RNA helicase DDX4; ATP-dependent RNA helicase required during spermatogenesis to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the secondary piRNAs metabolic process, the production of piRNAs in fetal male germ cells through a ping-pong amplification cycl [...] | Zinc finger and BTB domain containing 16. | 0.734 |
GFRA1 | DAZL | ENSSSCP00000048866 | ENSSSCP00000073353 | GDNF family receptor alpha 1. | Deleted in azoospermia-like protein. | 0.690 |
GFRA1 | DDX4 | ENSSSCP00000048866 | ENSSSCP00000063433 | GDNF family receptor alpha 1. | Probable ATP-dependent RNA helicase DDX4; ATP-dependent RNA helicase required during spermatogenesis to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the secondary piRNAs metabolic process, the production of piRNAs in fetal male germ cells through a ping-pong amplification cycl [...] | 0.603 |
GFRA1 | KIT | ENSSSCP00000048866 | ENSSSCP00000066488 | GDNF family receptor alpha 1. | Mast/stem cell growth factor receptor Kit; Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Phosphorylates PIK3R1, PLCG1, SH2B2/APS and CBL. Activates the AKT1 signaling pathway by phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase. Activat [...] | 0.559 |
GFRA1 | NANOS2 | ENSSSCP00000048866 | ENSSSCP00000003352 | GDNF family receptor alpha 1. | Nanos C2HC-type zinc finger 2; Belongs to the nanos family. | 0.635 |
GFRA1 | STRA8 | ENSSSCP00000048866 | ENSSSCP00000017519 | GDNF family receptor alpha 1. | Stimulated by retinoic acid 8. | 0.716 |
GFRA1 | SYCP3 | ENSSSCP00000048866 | ENSSSCP00000034487 | GDNF family receptor alpha 1. | Synaptonemal complex protein 3. | 0.577 |