STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TRPS1Transcriptional repressor GATA binding 1. (1294 aa)    
Predicted Functional Partners:
HDAC4
Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.
   
 
 0.568
IGSF11
Immunoglobulin superfamily member 11.
   
  
 0.557
NFYB
Nuclear transcription factor Y subunit beta isoform X1.
    
 
 0.520
RUNX2
Runt-related transcription factor 2 isoform a.
    
 
 0.488
LRRC14
Leucine-rich repeat-containing protein 14 isoform X1.
      
 0.487
WDR74
Uncharacterized protein.
      
 0.487
EDAR
Ectodysplasin A receptor.
      
 0.485
SOX18
SRY-box transcription factor 18.
    
 
 0.482
CLVS2
Clavesin 2.
      
 0.477
RABAC1
Prenylated Rab acceptor protein 1; General Rab protein regulator required for vesicle formation from the Golgi complex. May control vesicle docking and fusion by mediating the action of Rab GTPases to the SNARE complexes. In addition it inhibits the removal of Rab GTPases from the membrane by GDI1.
      
 0.473
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.