node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BRCA2 | SYCP3 | ENSSSCP00000028073 | ENSSSCP00000034487 | Tower domain-containing protein. | Synaptonemal complex protein 3. | 0.912 |
DDX4 | HORMAD1 | ENSSSCP00000063433 | ENSSSCP00000007090 | Probable ATP-dependent RNA helicase DDX4; ATP-dependent RNA helicase required during spermatogenesis to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the secondary piRNAs metabolic process, the production of piRNAs in fetal male germ cells through a ping-pong amplification cycl [...] | HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...] | 0.478 |
DDX4 | REC8 | ENSSSCP00000063433 | ENSSSCP00000002187 | Probable ATP-dependent RNA helicase DDX4; ATP-dependent RNA helicase required during spermatogenesis to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the secondary piRNAs metabolic process, the production of piRNAs in fetal male germ cells through a ping-pong amplification cycl [...] | Meiotic recombination protein REC8 homolog. | 0.485 |
DDX4 | STRA8 | ENSSSCP00000063433 | ENSSSCP00000017519 | Probable ATP-dependent RNA helicase DDX4; ATP-dependent RNA helicase required during spermatogenesis to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the secondary piRNAs metabolic process, the production of piRNAs in fetal male germ cells through a ping-pong amplification cycl [...] | Stimulated by retinoic acid 8. | 0.865 |
DDX4 | SYCE3 | ENSSSCP00000063433 | ENSSSCP00000001031 | Probable ATP-dependent RNA helicase DDX4; ATP-dependent RNA helicase required during spermatogenesis to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the secondary piRNAs metabolic process, the production of piRNAs in fetal male germ cells through a ping-pong amplification cycl [...] | Synaptonemal complex central element protein 3. | 0.435 |
DDX4 | SYCP3 | ENSSSCP00000063433 | ENSSSCP00000034487 | Probable ATP-dependent RNA helicase DDX4; ATP-dependent RNA helicase required during spermatogenesis to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the secondary piRNAs metabolic process, the production of piRNAs in fetal male germ cells through a ping-pong amplification cycl [...] | Synaptonemal complex protein 3. | 0.870 |
HORMAD1 | DDX4 | ENSSSCP00000007090 | ENSSSCP00000063433 | HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...] | Probable ATP-dependent RNA helicase DDX4; ATP-dependent RNA helicase required during spermatogenesis to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the secondary piRNAs metabolic process, the production of piRNAs in fetal male germ cells through a ping-pong amplification cycl [...] | 0.478 |
HORMAD1 | MSH4 | ENSSSCP00000007090 | ENSSSCP00000019449 | HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...] | MutS homolog 4. | 0.713 |
HORMAD1 | REC8 | ENSSSCP00000007090 | ENSSSCP00000002187 | HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...] | Meiotic recombination protein REC8 homolog. | 0.856 |
HORMAD1 | STAG3 | ENSSSCP00000007090 | ENSSSCP00000008171 | HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...] | Stromal antigen 3. | 0.800 |
HORMAD1 | STRA8 | ENSSSCP00000007090 | ENSSSCP00000017519 | HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...] | Stimulated by retinoic acid 8. | 0.578 |
HORMAD1 | SYCE2 | ENSSSCP00000007090 | ENSSSCP00000014609 | HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...] | Synaptonemal complex central element protein 2. | 0.682 |
HORMAD1 | SYCE3 | ENSSSCP00000007090 | ENSSSCP00000001031 | HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...] | Synaptonemal complex central element protein 3. | 0.800 |
HORMAD1 | SYCP3 | ENSSSCP00000007090 | ENSSSCP00000034487 | HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...] | Synaptonemal complex protein 3. | 0.884 |
HORMAD2 | MSH4 | ENSSSCP00000010667 | ENSSSCP00000019449 | HORMA domain containing 2. | MutS homolog 4. | 0.513 |
HORMAD2 | REC8 | ENSSSCP00000010667 | ENSSSCP00000002187 | HORMA domain containing 2. | Meiotic recombination protein REC8 homolog. | 0.548 |
HORMAD2 | STAG3 | ENSSSCP00000010667 | ENSSSCP00000008171 | HORMA domain containing 2. | Stromal antigen 3. | 0.503 |
HORMAD2 | STRA8 | ENSSSCP00000010667 | ENSSSCP00000017519 | HORMA domain containing 2. | Stimulated by retinoic acid 8. | 0.514 |
HORMAD2 | SYCE2 | ENSSSCP00000010667 | ENSSSCP00000014609 | HORMA domain containing 2. | Synaptonemal complex central element protein 2. | 0.517 |
HORMAD2 | SYCE3 | ENSSSCP00000010667 | ENSSSCP00000001031 | HORMA domain containing 2. | Synaptonemal complex central element protein 3. | 0.446 |