STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RXFP1Relaxin family peptide receptor 1. (785 aa)    
Predicted Functional Partners:
RLN2
Relaxin A chain; Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals.
     
 0.991
RLN3
Relaxin-3 A chain; May play a role in neuropeptide signaling processes. Ligand for LGR7, relaxin-3 receptor-1 and relaxin-3 receptor-2 (By similarity).
   
 
 0.990
RXFP4
Relaxin-3/INSL7 receptor 2.
     
 0.988
RXFP3
G_PROTEIN_RECEP_F1_2 domain-containing protein.
     
 0.987
INSL3
Insulin-like 3 A chain; Seems to play a role in testicular function. May be a trophic hormone with a role in testicular descent in fetal life. Is a ligand for LGR8 receptor (By similarity); Belongs to the insulin family.
    
 0.986
A0A5G2QVF6_PIG
G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.
     
 0.919
RXFP2
Relaxin family peptide receptor 2.
  
0.918
GNAO1
Guanine nucleotide-binding protein G(O) subunit alpha isoform b.
    
 0.912
GNAI3
Guanine nucleotide-binding protein G(K) subunit alpha.
    
 0.911
GNAI2
G protein subunit alpha i2.
    
 0.911
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.