node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BUB3 | CDC20 | ENSSSCP00000011435 | ENSSSCP00000004268 | BUB3 mitotic checkpoint protein. | Cell division cycle protein 20 homolog; Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 induces presynaptic differentia [...] | 0.996 |
BUB3 | CDK1 | ENSSSCP00000011435 | ENSSSCP00000044214 | BUB3 mitotic checkpoint protein. | Cyclin-dependent kinase 1 isoform 1; Belongs to the protein kinase superfamily. | 0.818 |
BUB3 | CLASP1 | ENSSSCP00000011435 | ENSSSCP00000034912 | BUB3 mitotic checkpoint protein. | Cytoplasmic linker associated protein 1. | 0.635 |
BUB3 | CLIP1 | ENSSSCP00000011435 | ENSSSCP00000010455 | BUB3 mitotic checkpoint protein. | CAP-Gly domain containing linker protein 1. | 0.654 |
BUB3 | KIF2B | ENSSSCP00000011435 | ENSSSCP00000018653 | BUB3 mitotic checkpoint protein. | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | 0.631 |
BUB3 | MAPRE1 | ENSSSCP00000011435 | ENSSSCP00000033290 | BUB3 mitotic checkpoint protein. | Microtubule associated protein RP/EB family member 1. | 0.737 |
BUB3 | NUDC | ENSSSCP00000011435 | ENSSSCP00000052911 | BUB3 mitotic checkpoint protein. | CS domain-containing protein. | 0.538 |
BUB3 | PLK1 | ENSSSCP00000011435 | ENSSSCP00000023889 | BUB3 mitotic checkpoint protein. | Serine/threonine-protein kinase PLK. | 0.795 |
CCDC181 | CLASP1 | ENSSSCP00000052269 | ENSSSCP00000034912 | Coiled-coil domain containing 181. | Cytoplasmic linker associated protein 1. | 0.754 |
CDC20 | BUB3 | ENSSSCP00000004268 | ENSSSCP00000011435 | Cell division cycle protein 20 homolog; Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 induces presynaptic differentia [...] | BUB3 mitotic checkpoint protein. | 0.996 |
CDC20 | CDK1 | ENSSSCP00000004268 | ENSSSCP00000044214 | Cell division cycle protein 20 homolog; Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 induces presynaptic differentia [...] | Cyclin-dependent kinase 1 isoform 1; Belongs to the protein kinase superfamily. | 0.987 |
CDC20 | CLASP1 | ENSSSCP00000004268 | ENSSSCP00000034912 | Cell division cycle protein 20 homolog; Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 induces presynaptic differentia [...] | Cytoplasmic linker associated protein 1. | 0.812 |
CDC20 | CLIP1 | ENSSSCP00000004268 | ENSSSCP00000010455 | Cell division cycle protein 20 homolog; Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 induces presynaptic differentia [...] | CAP-Gly domain containing linker protein 1. | 0.806 |
CDC20 | KIF2B | ENSSSCP00000004268 | ENSSSCP00000018653 | Cell division cycle protein 20 homolog; Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 induces presynaptic differentia [...] | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | 0.884 |
CDC20 | MAPRE1 | ENSSSCP00000004268 | ENSSSCP00000033290 | Cell division cycle protein 20 homolog; Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 induces presynaptic differentia [...] | Microtubule associated protein RP/EB family member 1. | 0.813 |
CDC20 | NUDC | ENSSSCP00000004268 | ENSSSCP00000052911 | Cell division cycle protein 20 homolog; Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 induces presynaptic differentia [...] | CS domain-containing protein. | 0.811 |
CDC20 | PLK1 | ENSSSCP00000004268 | ENSSSCP00000023889 | Cell division cycle protein 20 homolog; Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 induces presynaptic differentia [...] | Serine/threonine-protein kinase PLK. | 0.998 |
CDK1 | BUB3 | ENSSSCP00000044214 | ENSSSCP00000011435 | Cyclin-dependent kinase 1 isoform 1; Belongs to the protein kinase superfamily. | BUB3 mitotic checkpoint protein. | 0.818 |
CDK1 | CDC20 | ENSSSCP00000044214 | ENSSSCP00000004268 | Cyclin-dependent kinase 1 isoform 1; Belongs to the protein kinase superfamily. | Cell division cycle protein 20 homolog; Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 induces presynaptic differentia [...] | 0.987 |
CDK1 | CLASP1 | ENSSSCP00000044214 | ENSSSCP00000034912 | Cyclin-dependent kinase 1 isoform 1; Belongs to the protein kinase superfamily. | Cytoplasmic linker associated protein 1. | 0.851 |