STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FOXA2Hepatocyte nuclear factor 3-beta isoform 1. (463 aa)    
Predicted Functional Partners:
RPS6KB2
Non-specific serine/threonine protein kinase.
     
 0.906
RPS6KB1
Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.
     
 0.906
SOX17
SRY-box transcription factor 17.
   
 
 0.887
PAX6
Paired box 6.
   
  
 0.879
GATA6
Transcription factor GATA-6; Transcriptional activator that regulates SEMA3C and PLXNA2. May regulate genes that protect epithelial cells from bacterial infection. Involved in gene regulation specifically in the gastric epithelium. Involved in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions.
   
 
 0.876
LMX1A
LIM homeobox transcription factor 1 alpha.
    
 
 0.876
NANOG
Homeobox domain-containing protein.
      
 0.871
OTX2
Orthodenticle homeobox 2.
   
 
 0.839
CDX2
Homeobox domain-containing protein.
   
  
 0.834
MIXL1
Mix paired-like homeobox.
   
  
 0.821
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.