node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AP4M1 | AP5Z1 | ENSSSCP00000062848 | ENSSSCP00000074423 | AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...] | Adaptor related protein complex 5 subunit zeta 1. | 0.756 |
AP4M1 | ARL6IP1 | ENSSSCP00000062848 | ENSSSCP00000069479 | AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...] | ADP ribosylation factor like GTPase 6 interacting protein 1. | 0.579 |
AP4M1 | ARSI | ENSSSCP00000062848 | ENSSSCP00000015379 | AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...] | Arylsulfatase family member I. | 0.599 |
AP4M1 | C19orf12 | ENSSSCP00000062848 | ENSSSCP00000035328 | AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...] | Chromosome 19 open reading frame 12. | 0.546 |
AP4M1 | DDHD1 | ENSSSCP00000062848 | ENSSSCP00000070072 | AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...] | Phospholipase DDHD1 isoform c. | 0.462 |
AP4M1 | DDHD2 | ENSSSCP00000062848 | ENSSSCP00000016764 | AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...] | Phospholipase DDHD2 isoform 1. | 0.544 |
AP4M1 | FA2H | ENSSSCP00000062848 | ENSSSCP00000002933 | AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...] | Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] | 0.444 |
AP4M1 | GBA2 | ENSSSCP00000062848 | ENSSSCP00000005713 | AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...] | Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide. | 0.741 |
AP4M1 | WDR48 | ENSSSCP00000062848 | ENSSSCP00000068677 | AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...] | WD repeat domain 48. | 0.560 |
AP5Z1 | AP4M1 | ENSSSCP00000074423 | ENSSSCP00000062848 | Adaptor related protein complex 5 subunit zeta 1. | AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...] | 0.756 |
AP5Z1 | ARL6IP1 | ENSSSCP00000074423 | ENSSSCP00000069479 | Adaptor related protein complex 5 subunit zeta 1. | ADP ribosylation factor like GTPase 6 interacting protein 1. | 0.554 |
AP5Z1 | ARSI | ENSSSCP00000074423 | ENSSSCP00000015379 | Adaptor related protein complex 5 subunit zeta 1. | Arylsulfatase family member I. | 0.556 |
AP5Z1 | C19orf12 | ENSSSCP00000074423 | ENSSSCP00000035328 | Adaptor related protein complex 5 subunit zeta 1. | Chromosome 19 open reading frame 12. | 0.543 |
AP5Z1 | DDHD1 | ENSSSCP00000074423 | ENSSSCP00000070072 | Adaptor related protein complex 5 subunit zeta 1. | Phospholipase DDHD1 isoform c. | 0.502 |
AP5Z1 | DDHD2 | ENSSSCP00000074423 | ENSSSCP00000016764 | Adaptor related protein complex 5 subunit zeta 1. | Phospholipase DDHD2 isoform 1. | 0.546 |
AP5Z1 | FA2H | ENSSSCP00000074423 | ENSSSCP00000002933 | Adaptor related protein complex 5 subunit zeta 1. | Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] | 0.454 |
AP5Z1 | GBA2 | ENSSSCP00000074423 | ENSSSCP00000005713 | Adaptor related protein complex 5 subunit zeta 1. | Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide. | 0.688 |
AP5Z1 | WDR48 | ENSSSCP00000074423 | ENSSSCP00000068677 | Adaptor related protein complex 5 subunit zeta 1. | WD repeat domain 48. | 0.556 |
ARL6IP1 | AP4M1 | ENSSSCP00000069479 | ENSSSCP00000062848 | ADP ribosylation factor like GTPase 6 interacting protein 1. | AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...] | 0.579 |
ARL6IP1 | AP5Z1 | ENSSSCP00000069479 | ENSSSCP00000074423 | ADP ribosylation factor like GTPase 6 interacting protein 1. | Adaptor related protein complex 5 subunit zeta 1. | 0.554 |