STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A286ZVM6_PIGUncharacterized protein. (36 aa)    
Predicted Functional Partners:
CCL5
C-C motif chemokine 5; Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. May also be an agonist of the G protein-coupled receptor GPR75. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells. Belongs to the intercrine beta (chemokine CC) family.
    
 
 0.780
CXCL13
C-X-C motif chemokine.
    
 
 0.664
CCL26
C-C motif chemokine.
    
 
 0.657
CXCL12
C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family.
    
 
 0.633
CXCL14
SCY domain-containing protein.
    
 
 0.626
CCL11
C-C motif chemokine.
    
 
 0.605
CCL8
C-C motif chemokine 8; Chemotactic factor that attracts monocytes. This protein can bind heparin.
    
 
 0.605
LOC110260995
Uncharacterized protein.
    
 
 0.519
LOC100737180
C-X-C motif chemokine 17.
    
 
 0.519
CXCL9
C-X-C motif chemokine.
    
 
 0.430
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.