STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LIFLeukemia inhibitory factor isoform X1. (202 aa)    
Predicted Functional Partners:
LIFR
LIF receptor subunit alpha.
    
 0.987
IL6ST
Interleukin 6 signal transducer.
    
 0.962
OSM
Oncostatin M.
   
 
 0.877
CTF1
Cardiotrophin 1.
     
 0.864
IL12RB2
Interleukin-12 receptor subunit beta-2; Receptor for interleukin-12. This subunit is the signaling component coupling to the JAK2/STAT4 pathway; Belongs to the type I cytokine receptor family. Type 2 subfamily.
    
 0.838
IL27RA
Uncharacterized protein.
    
 0.838
FGF2
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
   
  
 0.790
NANOG
Homeobox domain-containing protein.
      
 0.785
IL5RA
Interleukin 5 receptor subunit alpha.
  
 
  0.769
CNTFR
Ciliary neurotrophic factor receptor.
     
 0.759
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.