STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A286ZZT1_PIGS5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (251 aa)    
Predicted Functional Partners:
RPSA
40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteri [...]
  
 0.999
RPS18
40S ribosomal protein S18; Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA; Belongs to the universal ribosomal protein uS13 family.
  
 0.998
RPS16
40S ribosomal protein S16; Belongs to the universal ribosomal protein uS9 family.
  
 0.998
RPS5
40S ribosomal protein S5; Belongs to the universal ribosomal protein uS7 family.
  
 0.998
RPS3
40S ribosomal protein S3; Involved in translation as a component of the 40S small ribosomal subunit. Has endonuclease activity and plays a role in repair of damaged DNA. Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA. Displays high binding affinity for 7,8- dihydro-8-oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS). Has also been shown to bind with similar affinity to intact and damaged DNA. Stimulates the N-glycosylase activity of the base excision protei [...]
  
 0.998
F1S4M2_PIG
Uncharacterized protein; Belongs to the universal ribosomal protein uS13 family.
  
 
 0.997
RPS29
40S ribosomal protein S29.
  
 0.997
A0A287BBK4_PIG
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
 0.997
RPL4
60S ribosomal protein L4; Belongs to the universal ribosomal protein uL4 family.
  
 
 0.997
RPS11
Ribosomal protein S11; Belongs to the universal ribosomal protein uS17 family.
  
 0.996
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.