STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLC35A5Solute carrier family 35 member A5. (396 aa)    
Predicted Functional Partners:
ITM2C
Integral membrane protein 2C; Negative regulator of amyloid-beta peptide production. May inhibit the processing of APP by blocking its access to alpha- and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation (By similarity).
   
  
 0.855
METTL21C
Methyltransferase like 21C.
      
 0.673
SLC35B1
Solute carrier family 35 member B1.
   
  
 0.657
PARM1
Uncharacterized protein.
      
 0.627
SLC35B3
Solute carrier family 35 member B3.
   
  
 0.576
SLC35F1
Solute carrier family 35 member F1.
      
 0.571
SLC35C2
Solute carrier family 35 member C2 isoform a.
   
  
 0.560
TTLL5
Tubulin tyrosine ligase like 5.
   
  
 0.548
MYH13
Myosin heavy chain 13; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
      
 0.547
SPATA6L
Spermatogenesis associated 6 like.
      
 0.546
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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