STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RASGEF1ARasGEF domain family member 1A. (494 aa)    
Predicted Functional Partners:
ZNHIT6
Box C/D snoRNA protein 1 isoform 1.
      
 0.725
KLHL5
Kelch like family member 5.
      
 0.684
ATP6V1C2
V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
      
 0.656
LRGUK
Leucine rich repeats and guanylate kinase domain containing.
      
 0.609
NMU
Neuromedin-U-25; Stimulates uterine smooth muscle contraction and causes selective vasoconstriction; Belongs to the NmU family.
      
 0.580
PIWIL1
Piwi like RNA-mediated gene silencing 1; Belongs to the argonaute family.
      
 0.572
HLCS
Holocarboxylase synthetase.
      
 0.547
ALDH1A1
Aldehyde dehydrogenase 1 family member A1; Belongs to the aldehyde dehydrogenase family.
      
 0.543
ANGPTL3
Fibrinogen C-terminal domain-containing protein.
   
  
 0.538
SULF2
Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family.
   
  
 0.529
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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