node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADGRF1 | FAAH | ENSSSCP00000001883 | ENSSSCP00000050676 | Adhesion G-protein coupled receptor F1 isoform 1; Belongs to the G-protein coupled receptor 2 family. | Fatty-acid amide hydrolase 1; Degrades bioactive fatty acid amides like oleamide, the endogenous cannabinoid, anandamide and myristic amide to their corresponding acids, thereby serving to terminate the signaling functions of these molecules. Hydrolyzes polyunsaturated substrate anandamide preferentially as compared to monounsaturated substrates (By similarity); Belongs to the amidase family. | 0.450 |
ADGRF1 | GPR119 | ENSSSCP00000001883 | ENSSSCP00000013460 | Adhesion G-protein coupled receptor F1 isoform 1; Belongs to the G-protein coupled receptor 2 family. | G protein-coupled receptor 119; Belongs to the G-protein coupled receptor 1 family. | 0.600 |
ADGRF1 | GPR18 | ENSSSCP00000001883 | ENSSSCP00000035963 | Adhesion G-protein coupled receptor F1 isoform 1; Belongs to the G-protein coupled receptor 2 family. | N-arachidonyl glycine receptor; Belongs to the G-protein coupled receptor 1 family. | 0.724 |
ADGRF1 | GPR55 | ENSSSCP00000001883 | ENSSSCP00000038940 | Adhesion G-protein coupled receptor F1 isoform 1; Belongs to the G-protein coupled receptor 2 family. | G-protein coupled receptor 55; Belongs to the G-protein coupled receptor 1 family. | 0.721 |
ADGRF1 | NAPEPLD | ENSSSCP00000001883 | ENSSSCP00000050861 | Adhesion G-protein coupled receptor F1 isoform 1; Belongs to the G-protein coupled receptor 2 family. | N-acyl phosphatidylethanolamine phospholipase D. | 0.403 |
CNR1 | CNR2 | ENSSSCP00000069188 | ENSSSCP00000061062 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | Cannabinoid receptor 2 isoform X1; Belongs to the G-protein coupled receptor 1 family. | 0.931 |
CNR1 | DAGLB | ENSSSCP00000069188 | ENSSSCP00000054600 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | Diacylglycerol lipase beta. | 0.458 |
CNR1 | FAAH | ENSSSCP00000069188 | ENSSSCP00000050676 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | Fatty-acid amide hydrolase 1; Degrades bioactive fatty acid amides like oleamide, the endogenous cannabinoid, anandamide and myristic amide to their corresponding acids, thereby serving to terminate the signaling functions of these molecules. Hydrolyzes polyunsaturated substrate anandamide preferentially as compared to monounsaturated substrates (By similarity); Belongs to the amidase family. | 0.873 |
CNR1 | GPR18 | ENSSSCP00000069188 | ENSSSCP00000035963 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | N-arachidonyl glycine receptor; Belongs to the G-protein coupled receptor 1 family. | 0.690 |
CNR1 | GPR55 | ENSSSCP00000069188 | ENSSSCP00000038940 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | G-protein coupled receptor 55; Belongs to the G-protein coupled receptor 1 family. | 0.812 |
CNR1 | LOC102164418 | ENSSSCP00000069188 | ENSSSCP00000046471 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | Amidase domain-containing protein. | 0.661 |
CNR1 | NAPEPLD | ENSSSCP00000069188 | ENSSSCP00000050861 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | N-acyl phosphatidylethanolamine phospholipase D. | 0.699 |
CNR1 | TRPV1 | ENSSSCP00000069188 | ENSSSCP00000058489 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family. | 0.621 |
CNR2 | CNR1 | ENSSSCP00000061062 | ENSSSCP00000069188 | Cannabinoid receptor 2 isoform X1; Belongs to the G-protein coupled receptor 1 family. | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | 0.931 |
CNR2 | DAGLB | ENSSSCP00000061062 | ENSSSCP00000054600 | Cannabinoid receptor 2 isoform X1; Belongs to the G-protein coupled receptor 1 family. | Diacylglycerol lipase beta. | 0.487 |
CNR2 | FAAH | ENSSSCP00000061062 | ENSSSCP00000050676 | Cannabinoid receptor 2 isoform X1; Belongs to the G-protein coupled receptor 1 family. | Fatty-acid amide hydrolase 1; Degrades bioactive fatty acid amides like oleamide, the endogenous cannabinoid, anandamide and myristic amide to their corresponding acids, thereby serving to terminate the signaling functions of these molecules. Hydrolyzes polyunsaturated substrate anandamide preferentially as compared to monounsaturated substrates (By similarity); Belongs to the amidase family. | 0.677 |
CNR2 | GPR18 | ENSSSCP00000061062 | ENSSSCP00000035963 | Cannabinoid receptor 2 isoform X1; Belongs to the G-protein coupled receptor 1 family. | N-arachidonyl glycine receptor; Belongs to the G-protein coupled receptor 1 family. | 0.637 |
CNR2 | GPR55 | ENSSSCP00000061062 | ENSSSCP00000038940 | Cannabinoid receptor 2 isoform X1; Belongs to the G-protein coupled receptor 1 family. | G-protein coupled receptor 55; Belongs to the G-protein coupled receptor 1 family. | 0.748 |
CNR2 | LOC102164418 | ENSSSCP00000061062 | ENSSSCP00000046471 | Cannabinoid receptor 2 isoform X1; Belongs to the G-protein coupled receptor 1 family. | Amidase domain-containing protein. | 0.607 |
CNR2 | NAPEPLD | ENSSSCP00000061062 | ENSSSCP00000050861 | Cannabinoid receptor 2 isoform X1; Belongs to the G-protein coupled receptor 1 family. | N-acyl phosphatidylethanolamine phospholipase D. | 0.625 |