STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CD19CD19 molecule. (645 aa)    
Predicted Functional Partners:
CD81
Tetraspanin.
    
 0.999
LYN
Tyrosine-protein kinase.
   
 0.989
CD79A
Ig-like domain-containing protein.
   
 
 0.984
VAV1
Vav guanine nucleotide exchange factor 1.
   
 0.965
SYK
40 kDa tyrosine-protein kinase SYK; Non-receptor tyrosine kinase which mediates signal transduction downstream of a variety of transmembrane receptors including classical immunoreceptors like the B-cell receptor (BCR). Regulates several biological processes including innate and adaptive immunity, cell adhesion, osteoclast maturation, platelet activation and vascular development. Assembles into signaling complexes with activated receptors at the plasma membrane via interaction between its SH2 domains and the receptor tyrosine-phosphorylated ITAM domains. The association with the recepto [...]
   
 0.960
CXCR5
C-X-C chemokine receptor type 5 isoform 1; Belongs to the G-protein coupled receptor 1 family.
   
  
 0.958
CD4
CD4 molecule.
   
  
 0.943
CD44
CD44 molecule (Indian blood group).
      
 0.938
VAV3
Vav guanine nucleotide exchange factor 3.
   
 0.936
VAV2
Vav guanine nucleotide exchange factor 2.
   
 0.936
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.