STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPIRE1Spire type actin nucleation factor 1. (802 aa)    
Predicted Functional Partners:
FMN2
FH2 domain-containing protein.
    
 
 0.915
FMN1
Formin 1.
    
 
 0.744
MFSD11
Major facilitator superfamily domain containing 11.
    
 
 0.682
SEC14L1
SEC14 like lipid binding 1.
    
 
 0.681
METTL23
Methyltransferase like 23.
    
 
 0.678
GRAP2
GRB2-related adapter protein 2 isoform 1.
   
 
 0.647
MYO5B
Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
 
 0.641
INF2
Uncharacterized protein.
    
 
 0.618
GREB1L
GREB1 like retinoic acid receptor coactivator.
      
 0.571
MGAT5B
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B isoform 3.
   
  
 0.558
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.