HNRNPH2 protein (Sus scrofa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

HNRNPH2

Heterogeneous nuclear ribonucleoprotein H2. (449 aa)

Predicted Functional Partners:

HNRNPC

0.784

HNRNPU

0.771

HNRNPK

0.756

SRSF1

0.750

FUS

0.742

HNRNPL

0.738

SRSF9

0.735

SRSF3

0.723

HNRNPA1

0.699

HNRNPM

0.696

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FUS	HNRNPA1	ENSSSCP00000031028	ENSSSCP00000033484	FUS RNA binding protein.	Heterogeneous nuclear ribonucleoprotein A1.	0.700
FUS	HNRNPC	ENSSSCP00000031028	ENSSSCP00000024485	FUS RNA binding protein.	Heterogeneous nuclear ribonucleoproteins C1/C2 isoform X1.	0.793
FUS	HNRNPH2	ENSSSCP00000031028	ENSSSCP00000040592	FUS RNA binding protein.	Heterogeneous nuclear ribonucleoprotein H2.	0.742
FUS	HNRNPK	ENSSSCP00000031028	ENSSSCP00000026450	FUS RNA binding protein.	Uncharacterized protein.	0.815
FUS	HNRNPL	ENSSSCP00000031028	ENSSSCP00000044313	FUS RNA binding protein.	Heterogeneous nuclear ribonucleoprotein L.	0.658
FUS	HNRNPM	ENSSSCP00000031028	ENSSSCP00000014455	FUS RNA binding protein.	Heterogeneous nuclear ribonucleoprotein M.	0.618
FUS	HNRNPU	ENSSSCP00000031028	ENSSSCP00000035493	FUS RNA binding protein.	Heterogeneous nuclear ribonucleoprotein U isoform a.	0.729
FUS	SRSF1	ENSSSCP00000031028	ENSSSCP00000057405	FUS RNA binding protein.	Serine/arginine-rich splicing factor 1; Plays a role in preventing exon skipping, ensuring the accuracy of splicing and regulating alternative splicing. Interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF. Can stimulate binding of U1 snRNP to a 5'-splice site- containing pre-mRNA. Binds to purine-rich RNA sequences, either the octamer, 5'-RGAAGAAC-3' (r=A or G) or the decamers, AGGACAGAGC/AGGACGAAGC. Binds preferentially to the 5'-CGAGGCG-3' motif in vitro. Three copies of the octame [...]	0.806
FUS	SRSF3	ENSSSCP00000031028	ENSSSCP00000001699	FUS RNA binding protein.	Serine and arginine rich splicing factor 3.	0.695
FUS	SRSF9	ENSSSCP00000031028	ENSSSCP00000010572	FUS RNA binding protein.	Uncharacterized protein.	0.542
HNRNPA1	FUS	ENSSSCP00000033484	ENSSSCP00000031028	Heterogeneous nuclear ribonucleoprotein A1.	FUS RNA binding protein.	0.700
HNRNPA1	HNRNPC	ENSSSCP00000033484	ENSSSCP00000024485	Heterogeneous nuclear ribonucleoprotein A1.	Heterogeneous nuclear ribonucleoproteins C1/C2 isoform X1.	0.963
HNRNPA1	HNRNPH2	ENSSSCP00000033484	ENSSSCP00000040592	Heterogeneous nuclear ribonucleoprotein A1.	Heterogeneous nuclear ribonucleoprotein H2.	0.699
HNRNPA1	HNRNPK	ENSSSCP00000033484	ENSSSCP00000026450	Heterogeneous nuclear ribonucleoprotein A1.	Uncharacterized protein.	0.976
HNRNPA1	HNRNPL	ENSSSCP00000033484	ENSSSCP00000044313	Heterogeneous nuclear ribonucleoprotein A1.	Heterogeneous nuclear ribonucleoprotein L.	0.778
HNRNPA1	HNRNPM	ENSSSCP00000033484	ENSSSCP00000014455	Heterogeneous nuclear ribonucleoprotein A1.	Heterogeneous nuclear ribonucleoprotein M.	0.973
HNRNPA1	HNRNPU	ENSSSCP00000033484	ENSSSCP00000035493	Heterogeneous nuclear ribonucleoprotein A1.	Heterogeneous nuclear ribonucleoprotein U isoform a.	0.816
HNRNPA1	SRSF1	ENSSSCP00000033484	ENSSSCP00000057405	Heterogeneous nuclear ribonucleoprotein A1.	Serine/arginine-rich splicing factor 1; Plays a role in preventing exon skipping, ensuring the accuracy of splicing and regulating alternative splicing. Interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF. Can stimulate binding of U1 snRNP to a 5'-splice site- containing pre-mRNA. Binds to purine-rich RNA sequences, either the octamer, 5'-RGAAGAAC-3' (r=A or G) or the decamers, AGGACAGAGC/AGGACGAAGC. Binds preferentially to the 5'-CGAGGCG-3' motif in vitro. Three copies of the octame [...]	0.868
HNRNPA1	SRSF3	ENSSSCP00000033484	ENSSSCP00000001699	Heterogeneous nuclear ribonucleoprotein A1.	Serine and arginine rich splicing factor 3.	0.686
HNRNPA1	SRSF9	ENSSSCP00000033484	ENSSSCP00000010572	Heterogeneous nuclear ribonucleoprotein A1.	Uncharacterized protein.	0.649