STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MOSMOModulator of smoothened. (167 aa)    
Predicted Functional Partners:
SMO
Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.
     
 0.919
MEGF8
Multiple EGF like domains 8.
      
 0.675
VWA3A
Von Willebrand factor A domain containing 3A.
 
    
 0.635
RNF157
Ring finger protein 157.
      
 0.572
CLDN19
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
      
 0.571
FAM20B
FAM20B glycosaminoglycan xylosylkinase.
      
 0.537
LHFPL4
LHFPL tetraspan subfamily member 4 protein isoform X1.
      
 0.532
LHFPL3
LHFPL tetraspan subfamily member 3.
      
 0.532
ATRNL1
Attractin like 1.
      
 0.516
POLR3E
RNA polymerase III subunit E.
      
 0.515
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.