node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALPK3 | ATP8B2 | ENSSSCP00000041544 | ENSSSCP00000023915 | Alpha-type protein kinase domain-containing protein. | Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. | 0.787 |
ALPK3 | BOD1L1 | ENSSSCP00000041544 | ENSSSCP00000031288 | Alpha-type protein kinase domain-containing protein. | Biorientation of chromosomes in cell division protein 1-like 1. | 0.681 |
ALPK3 | CCDC174 | ENSSSCP00000041544 | ENSSSCP00000049946 | Alpha-type protein kinase domain-containing protein. | Uncharacterized protein. | 0.789 |
ALPK3 | GRB10 | ENSSSCP00000041544 | ENSSSCP00000031279 | Alpha-type protein kinase domain-containing protein. | Growth factor receptor-bound protein 10; Adapter protein which modulates coupling of a number of cell surface receptor kinases with specific signaling pathways. Binds to, and suppress signals from, activated receptors tyrosine kinases, including the insulin (INSR) and insulin-like growth factor (IGF1R) receptors. The inhibitory effect can be achieved by 2 mechanisms: interference with the signaling pathway and increased receptor degradation. Delays and reduces AKT1 phosphorylation in response to insulin stimulation. Blocks association between INSR and IRS1 and IRS2 and prevents insulin [...] | 0.658 |
ALPK3 | MED12 | ENSSSCP00000041544 | ENSSSCP00000044257 | Alpha-type protein kinase domain-containing protein. | Mediator complex subunit 12. | 0.660 |
ALPK3 | OBSL1 | ENSSSCP00000041544 | ENSSSCP00000052588 | Alpha-type protein kinase domain-containing protein. | Obscurin-like protein 1 isoform X2. | 0.827 |
ALPK3 | PKD1L2 | ENSSSCP00000041544 | ENSSSCP00000040754 | Alpha-type protein kinase domain-containing protein. | Uncharacterized protein. | 0.763 |
ALPK3 | PLAG1 | ENSSSCP00000041544 | ENSSSCP00000006660 | Alpha-type protein kinase domain-containing protein. | PLAG1 zinc finger. | 0.673 |
ALPK3 | SLC25A44 | ENSSSCP00000041544 | ENSSSCP00000062466 | Alpha-type protein kinase domain-containing protein. | Solute carrier family 25 member 44; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.665 |
ALPK3 | TMEM150A | ENSSSCP00000041544 | ENSSSCP00000040062 | Alpha-type protein kinase domain-containing protein. | Transmembrane protein 150A. | 0.665 |
ATP8B2 | ALPK3 | ENSSSCP00000023915 | ENSSSCP00000041544 | Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. | Alpha-type protein kinase domain-containing protein. | 0.787 |
ATP8B2 | BOD1L1 | ENSSSCP00000023915 | ENSSSCP00000031288 | Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. | Biorientation of chromosomes in cell division protein 1-like 1. | 0.734 |
BOD1L1 | ALPK3 | ENSSSCP00000031288 | ENSSSCP00000041544 | Biorientation of chromosomes in cell division protein 1-like 1. | Alpha-type protein kinase domain-containing protein. | 0.681 |
BOD1L1 | ATP8B2 | ENSSSCP00000031288 | ENSSSCP00000023915 | Biorientation of chromosomes in cell division protein 1-like 1. | Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. | 0.734 |
CCDC174 | ALPK3 | ENSSSCP00000049946 | ENSSSCP00000041544 | Uncharacterized protein. | Alpha-type protein kinase domain-containing protein. | 0.789 |
GRB10 | ALPK3 | ENSSSCP00000031279 | ENSSSCP00000041544 | Growth factor receptor-bound protein 10; Adapter protein which modulates coupling of a number of cell surface receptor kinases with specific signaling pathways. Binds to, and suppress signals from, activated receptors tyrosine kinases, including the insulin (INSR) and insulin-like growth factor (IGF1R) receptors. The inhibitory effect can be achieved by 2 mechanisms: interference with the signaling pathway and increased receptor degradation. Delays and reduces AKT1 phosphorylation in response to insulin stimulation. Blocks association between INSR and IRS1 and IRS2 and prevents insulin [...] | Alpha-type protein kinase domain-containing protein. | 0.658 |
GRB10 | MED12 | ENSSSCP00000031279 | ENSSSCP00000044257 | Growth factor receptor-bound protein 10; Adapter protein which modulates coupling of a number of cell surface receptor kinases with specific signaling pathways. Binds to, and suppress signals from, activated receptors tyrosine kinases, including the insulin (INSR) and insulin-like growth factor (IGF1R) receptors. The inhibitory effect can be achieved by 2 mechanisms: interference with the signaling pathway and increased receptor degradation. Delays and reduces AKT1 phosphorylation in response to insulin stimulation. Blocks association between INSR and IRS1 and IRS2 and prevents insulin [...] | Mediator complex subunit 12. | 0.594 |
GRB10 | OBSL1 | ENSSSCP00000031279 | ENSSSCP00000052588 | Growth factor receptor-bound protein 10; Adapter protein which modulates coupling of a number of cell surface receptor kinases with specific signaling pathways. Binds to, and suppress signals from, activated receptors tyrosine kinases, including the insulin (INSR) and insulin-like growth factor (IGF1R) receptors. The inhibitory effect can be achieved by 2 mechanisms: interference with the signaling pathway and increased receptor degradation. Delays and reduces AKT1 phosphorylation in response to insulin stimulation. Blocks association between INSR and IRS1 and IRS2 and prevents insulin [...] | Obscurin-like protein 1 isoform X2. | 0.690 |
GRB10 | PLAG1 | ENSSSCP00000031279 | ENSSSCP00000006660 | Growth factor receptor-bound protein 10; Adapter protein which modulates coupling of a number of cell surface receptor kinases with specific signaling pathways. Binds to, and suppress signals from, activated receptors tyrosine kinases, including the insulin (INSR) and insulin-like growth factor (IGF1R) receptors. The inhibitory effect can be achieved by 2 mechanisms: interference with the signaling pathway and increased receptor degradation. Delays and reduces AKT1 phosphorylation in response to insulin stimulation. Blocks association between INSR and IRS1 and IRS2 and prevents insulin [...] | PLAG1 zinc finger. | 0.791 |
GRB10 | SLC25A44 | ENSSSCP00000031279 | ENSSSCP00000062466 | Growth factor receptor-bound protein 10; Adapter protein which modulates coupling of a number of cell surface receptor kinases with specific signaling pathways. Binds to, and suppress signals from, activated receptors tyrosine kinases, including the insulin (INSR) and insulin-like growth factor (IGF1R) receptors. The inhibitory effect can be achieved by 2 mechanisms: interference with the signaling pathway and increased receptor degradation. Delays and reduces AKT1 phosphorylation in response to insulin stimulation. Blocks association between INSR and IRS1 and IRS2 and prevents insulin [...] | Solute carrier family 25 member 44; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.428 |