STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C12orf73Chromosome 12 open reading frame 73. (71 aa)    
Predicted Functional Partners:
SFXN2
Sidoreflexin.
   
 
 0.732
RALGPS1
Ral GEF with PH domain and SH3 binding motif 1.
      
 0.722
MTBP
MDM2 binding protein.
      
 0.670
MTMR8
Myotubularin-related protein 8.
      
 0.663
PRRC2A
BAT2_N domain-containing protein.
      
 0.611
RNF14
RBR-type E3 ubiquitin transferase.
      
 0.611
COLQ
Collagen like tail subunit of asymmetric acetylcholinesterase.
      
 0.611
DNAJB14
DnaJ heat shock protein family (Hsp40) member B14.
      
 0.610
MAGED1
Melanoma-associated antigen D1; Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Inhibits cell cycle progression, and facilitates NGFR-mediated apoptosis. May act as a regulator of the function of DLX family members. May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl- conjugating enzyme (E2) at the E3:substrate complex. Plays a role in the circadian rhythm regulation. May act as RORA co-regulator, modulating the expression [...]
      
 0.547
ABCF3
ATP-binding cassette sub-family F member 3 isoform 1.
      
 0.547
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.