STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DCAF8DDB1 and CUL4 associated factor 8. (639 aa)    
Predicted Functional Partners:
DDB1
Damage specific DNA binding protein 1.
    
 0.927
CUL4A
Cullin 4A; Belongs to the cullin family.
   
 0.817
DCAF4
WD_REPEATS_REGION domain-containing protein.
     
 0.794
CUL4B
Cullin 4B; Belongs to the cullin family.
   
 0.792
DCAF12
DDB1 and CUL4 associated factor 12.
     
 0.762
DCAF11
DDB1- and CUL4-associated factor 11; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; Belongs to the WD repeat LEC14B family.
    
 0.739
LOC102159347
CULLIN_2 domain-containing protein; Belongs to the cullin family.
   
 0.677
TRPC4AP
Transient receptor potential cation channel subfamily C member 4 associated protein.
    
 0.658
APCDD1L
APC down-regulated 1 like.
      
 0.654
DCAF5
DDB1 and CUL4 associated factor 5.
   
 
0.648
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.