node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADCYAP1R1 | GNAS-2 | ENSSSCP00000043415 | ENSSSCP00000029022 | Pituitary adenylate cyclase-activating polypeptide type I receptor short form; Belongs to the G-protein coupled receptor 2 family. | Guanine nucleotide-binding protein G(s) subunit alpha. | 0.908 |
ADCYAP1R1 | GNB3 | ENSSSCP00000043415 | ENSSSCP00000000727 | Pituitary adenylate cyclase-activating polypeptide type I receptor short form; Belongs to the G-protein coupled receptor 2 family. | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform 1. | 0.931 |
ADCYAP1R1 | LOC110255211 | ENSSSCP00000043415 | ENSSSCP00000041932 | Pituitary adenylate cyclase-activating polypeptide type I receptor short form; Belongs to the G-protein coupled receptor 2 family. | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.920 |
CNR1 | DRD2 | ENSSSCP00000069188 | ENSSSCP00000049999 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. | 0.927 |
CNR1 | GNAO1 | ENSSSCP00000069188 | ENSSSCP00000040441 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | Guanine nucleotide-binding protein G(O) subunit alpha isoform b. | 0.931 |
CNR1 | GNB3 | ENSSSCP00000069188 | ENSSSCP00000000727 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform 1. | 0.922 |
CNR1 | LOC110255211 | ENSSSCP00000069188 | ENSSSCP00000041932 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.909 |
CNR1 | MTNR1A | ENSSSCP00000069188 | ENSSSCP00000053039 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | Melatonin receptor type 1A; High affinity receptor for melatonin. Likely to mediate the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity; Belongs to the G-protein coupled receptor 1 family. | 0.507 |
CNR1 | MTNR1B | ENSSSCP00000069188 | ENSSSCP00000015860 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | Melatonin receptor 1B; Belongs to the G-protein coupled receptor 1 family. | 0.507 |
DRD2 | CNR1 | ENSSSCP00000049999 | ENSSSCP00000069188 | Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | 0.927 |
DRD2 | GNAO1 | ENSSSCP00000049999 | ENSSSCP00000040441 | Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. | Guanine nucleotide-binding protein G(O) subunit alpha isoform b. | 0.968 |
DRD2 | GNB3 | ENSSSCP00000049999 | ENSSSCP00000000727 | Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform 1. | 0.940 |
DRD2 | LOC110255211 | ENSSSCP00000049999 | ENSSSCP00000041932 | Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.920 |
DRD3 | GNAO1 | ENSSSCP00000012691 | ENSSSCP00000040441 | Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. | Guanine nucleotide-binding protein G(O) subunit alpha isoform b. | 0.955 |
DRD3 | GNB3 | ENSSSCP00000012691 | ENSSSCP00000000727 | Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform 1. | 0.943 |
DRD3 | LOC110255211 | ENSSSCP00000012691 | ENSSSCP00000041932 | Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.920 |
GNAO1 | CNR1 | ENSSSCP00000040441 | ENSSSCP00000069188 | Guanine nucleotide-binding protein G(O) subunit alpha isoform b. | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | 0.931 |
GNAO1 | DRD2 | ENSSSCP00000040441 | ENSSSCP00000049999 | Guanine nucleotide-binding protein G(O) subunit alpha isoform b. | Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. | 0.968 |
GNAO1 | DRD3 | ENSSSCP00000040441 | ENSSSCP00000012691 | Guanine nucleotide-binding protein G(O) subunit alpha isoform b. | Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. | 0.955 |
GNAO1 | GNB3 | ENSSSCP00000040441 | ENSSSCP00000000727 | Guanine nucleotide-binding protein G(O) subunit alpha isoform b. | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform 1. | 0.979 |