LMNB2 protein (Sus scrofa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

LMNB2

Lamin B2; Belongs to the intermediate filament family. (742 aa)

Predicted Functional Partners:

LMNA

0.974

LMNB1

0.946

EMD

0.937

CASP6

0.924

LOC100739080

0.901

SUN2

0.843

LBR

0.777

BANF1

0.734

A0A287ADF8_PIG

0.734

ZNF570

0.727

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A287ADF8_PIG	EMD	ENSSSCP00000041845	ENSSSCP00000070492	Uncharacterized protein.	LEM domain-containing protein.	0.899
A0A287ADF8_PIG	LBR	ENSSSCP00000041845	ENSSSCP00000046854	Uncharacterized protein.	Lamin-B receptor.	0.573
A0A287ADF8_PIG	LMNA	ENSSSCP00000041845	ENSSSCP00000047557	Uncharacterized protein.	Prelamin-A/C; Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin A and C are present in equal amounts in the lamina of mammals. Plays an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics. Required for normal development of peripheral nervous system and skeletal muscle and for muscle satellite cell proliferation. Required for osteoblastogenesis and bone formation. A [...]	0.824
A0A287ADF8_PIG	LMNB1	ENSSSCP00000041845	ENSSSCP00000015156	Uncharacterized protein.	Lamin-B1 isoform 1; Belongs to the intermediate filament family.	0.733
A0A287ADF8_PIG	LMNB2	ENSSSCP00000041845	ENSSSCP00000042197	Uncharacterized protein.	Lamin B2; Belongs to the intermediate filament family.	0.734
BANF1	EMD	ENSSSCP00000023940	ENSSSCP00000070492	Barrier to autointegration factor 1.	LEM domain-containing protein.	0.968
BANF1	LBR	ENSSSCP00000023940	ENSSSCP00000046854	Barrier to autointegration factor 1.	Lamin-B receptor.	0.573
BANF1	LMNA	ENSSSCP00000023940	ENSSSCP00000047557	Barrier to autointegration factor 1.	Prelamin-A/C; Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin A and C are present in equal amounts in the lamina of mammals. Plays an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics. Required for normal development of peripheral nervous system and skeletal muscle and for muscle satellite cell proliferation. Required for osteoblastogenesis and bone formation. A [...]	0.908
BANF1	LMNB1	ENSSSCP00000023940	ENSSSCP00000015156	Barrier to autointegration factor 1.	Lamin-B1 isoform 1; Belongs to the intermediate filament family.	0.860
BANF1	LMNB2	ENSSSCP00000023940	ENSSSCP00000042197	Barrier to autointegration factor 1.	Lamin B2; Belongs to the intermediate filament family.	0.734
CASP6	LMNA	ENSSSCP00000068855	ENSSSCP00000047557	Caspase 6; Belongs to the peptidase C14A family.	Prelamin-A/C; Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin A and C are present in equal amounts in the lamina of mammals. Plays an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics. Required for normal development of peripheral nervous system and skeletal muscle and for muscle satellite cell proliferation. Required for osteoblastogenesis and bone formation. A [...]	0.935
CASP6	LMNB1	ENSSSCP00000068855	ENSSSCP00000015156	Caspase 6; Belongs to the peptidase C14A family.	Lamin-B1 isoform 1; Belongs to the intermediate filament family.	0.919
CASP6	LMNB2	ENSSSCP00000068855	ENSSSCP00000042197	Caspase 6; Belongs to the peptidase C14A family.	Lamin B2; Belongs to the intermediate filament family.	0.924
EMD	A0A287ADF8_PIG	ENSSSCP00000070492	ENSSSCP00000041845	LEM domain-containing protein.	Uncharacterized protein.	0.899
EMD	BANF1	ENSSSCP00000070492	ENSSSCP00000023940	LEM domain-containing protein.	Barrier to autointegration factor 1.	0.968
EMD	LBR	ENSSSCP00000070492	ENSSSCP00000046854	LEM domain-containing protein.	Lamin-B receptor.	0.934
EMD	LMNA	ENSSSCP00000070492	ENSSSCP00000047557	LEM domain-containing protein.	Prelamin-A/C; Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin A and C are present in equal amounts in the lamina of mammals. Plays an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics. Required for normal development of peripheral nervous system and skeletal muscle and for muscle satellite cell proliferation. Required for osteoblastogenesis and bone formation. A [...]	0.992
EMD	LMNB1	ENSSSCP00000070492	ENSSSCP00000015156	LEM domain-containing protein.	Lamin-B1 isoform 1; Belongs to the intermediate filament family.	0.985
EMD	LMNB2	ENSSSCP00000070492	ENSSSCP00000042197	LEM domain-containing protein.	Lamin B2; Belongs to the intermediate filament family.	0.937
EMD	SUN2	ENSSSCP00000070492	ENSSSCP00000056213	LEM domain-containing protein.	Sad1 and UNC84 domain containing 2.	0.864