STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A287AI89_PIGMetallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (60 aa)    
Predicted Functional Partners:
SLC30A1
Solute carrier family 30 member 1.
      
 0.763
ATOX1
HMA domain-containing protein.
   
  
 0.676
ATP7A
ATPase copper transporting alpha.
      
 0.647
COX17
Cytochrome c oxidase copper chaperone; Copper metallochaperone essential for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. Binds two copper ions and delivers them to the metallochaperone SCO1 which transports the copper ions to the Cu(A) site on the cytochrome c oxidase subunit II (MT-CO2/COX2).
      
 0.620
MT3
Metallothionein-3; Binds heavy metals. Contains three zinc and three copper atoms per polypeptide chain and only a negligible amount of cadmium. Inhibits survival and neurite formation of cortical neurons in vitro (By similarity); Belongs to the metallothionein superfamily. Type 1 family.
  
   
 0.602
SLC31A1
High affinity copper uptake protein 1; High-affinity, saturable copper transporter involved in dietary copper uptake.
   
 
 0.526
LOC100158001
Uncharacterized protein; Belongs to the multicopper oxidase family.
      
 0.496
CP
Ceruloplasmin; Belongs to the multicopper oxidase family.
      
 0.496
CCS
Copper chaperone for superoxide dismutase; Delivers copper to copper zinc superoxide dismutase (SOD1). In the C-terminal section; belongs to the Cu-Zn superoxide dismutase family.
      
 0.482
SLC30A8
Solute carrier family 30 member 8.
   
  
 0.480
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.