STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPATA6LSpermatogenesis associated 6 like. (409 aa)    
Predicted Functional Partners:
TTLL5
Tubulin tyrosine ligase like 5.
      
 0.848
DPY19L2
Dpy-19 like 2.
      
 0.727
IQCG
IQ domain-containing protein G isoform a.
      
 0.718
SMC1B
Structural maintenance of chromosomes protein.
      
 0.686
IFT81
Intraflagellar transport 81.
      
 0.670
SLC26A8
Solute carrier family 26 member 8.
      
 0.642
SLC35A5
Solute carrier family 35 member A5.
      
 0.546
SPO11
SPO11 meiotic protein covalently bound to DSB-like (S. cerevisiae).
      
 0.543
ITM2C
Integral membrane protein 2C; Negative regulator of amyloid-beta peptide production. May inhibit the processing of APP by blocking its access to alpha- and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation (By similarity).
      
 0.541
DEPDC5
DEP domain-containing protein.
      
 0.505
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.