node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
A0A287ALX3_PIG | ALB | ENSSSCP00000044902 | ENSSSCP00000053712 | Uncharacterized protein. | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | 0.518 |
A0A287ALX3_PIG | AMN | ENSSSCP00000044902 | ENSSSCP00000002732 | Uncharacterized protein. | Soluble protein amnionless; Membrane-bound component of the endocytic receptor formed by AMN and CUBN. Required for normal CUBN glycosylation and trafficking to the cell surface. The complex formed by AMN and CUBN is required for efficient absorption of vitamin B12. Required for normal CUBN-mediated protein transport in the kidney (By similarity). | 0.805 |
A0A287ALX3_PIG | ENOX1 | ENSSSCP00000044902 | ENSSSCP00000054653 | Uncharacterized protein. | Ecto-NOX disulfide-thiol exchanger 1. | 0.491 |
A0A287ALX3_PIG | GC | ENSSSCP00000044902 | ENSSSCP00000043366 | Uncharacterized protein. | GC vitamin D binding protein. | 0.602 |
A0A287ALX3_PIG | HP | ENSSSCP00000044902 | ENSSSCP00000043076 | Uncharacterized protein. | Haptoglobin alpha chain; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pat [...] | 0.506 |
A0A287ALX3_PIG | PDZK1 | ENSSSCP00000044902 | ENSSSCP00000024258 | Uncharacterized protein. | PDZ domain containing 1. | 0.528 |
A0A287ALX3_PIG | SLC17A1 | ENSSSCP00000044902 | ENSSSCP00000040019 | Uncharacterized protein. | Sodium-dependent phosphate transport protein 1 isoform X1. | 0.574 |
A0A287ALX3_PIG | TCN1 | ENSSSCP00000044902 | ENSSSCP00000037395 | Uncharacterized protein. | Transcobalamin-1; Binds vitamin B12 with femtomolar affinity and protects it from the acidic environment of the stomach (By similarity). Binds to cobalamin and to cobalamin analogs such as cobinamide; Belongs to the eukaryotic cobalamin transport proteins family. | 0.609 |
A0A287ALX3_PIG | TCN2 | ENSSSCP00000044902 | ENSSSCP00000010682 | Uncharacterized protein. | Transcobalamin-2 isoform 1. | 0.540 |
A0A287ALX3_PIG | TOM1L1 | ENSSSCP00000044902 | ENSSSCP00000018654 | Uncharacterized protein. | Target of myb1 like 1 membrane trafficking protein; Belongs to the TOM1 family. | 0.485 |
ALB | A0A287ALX3_PIG | ENSSSCP00000053712 | ENSSSCP00000044902 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Uncharacterized protein. | 0.518 |
ALB | GC | ENSSSCP00000053712 | ENSSSCP00000043366 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | GC vitamin D binding protein. | 0.699 |
ALB | HP | ENSSSCP00000053712 | ENSSSCP00000043076 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Haptoglobin alpha chain; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pat [...] | 0.924 |
AMN | A0A287ALX3_PIG | ENSSSCP00000002732 | ENSSSCP00000044902 | Soluble protein amnionless; Membrane-bound component of the endocytic receptor formed by AMN and CUBN. Required for normal CUBN glycosylation and trafficking to the cell surface. The complex formed by AMN and CUBN is required for efficient absorption of vitamin B12. Required for normal CUBN-mediated protein transport in the kidney (By similarity). | Uncharacterized protein. | 0.805 |
ENOX1 | A0A287ALX3_PIG | ENSSSCP00000054653 | ENSSSCP00000044902 | Ecto-NOX disulfide-thiol exchanger 1. | Uncharacterized protein. | 0.491 |
ENOX1 | TOM1L1 | ENSSSCP00000054653 | ENSSSCP00000018654 | Ecto-NOX disulfide-thiol exchanger 1. | Target of myb1 like 1 membrane trafficking protein; Belongs to the TOM1 family. | 0.730 |
GC | A0A287ALX3_PIG | ENSSSCP00000043366 | ENSSSCP00000044902 | GC vitamin D binding protein. | Uncharacterized protein. | 0.602 |
GC | ALB | ENSSSCP00000043366 | ENSSSCP00000053712 | GC vitamin D binding protein. | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | 0.699 |
GC | HP | ENSSSCP00000043366 | ENSSSCP00000043076 | GC vitamin D binding protein. | Haptoglobin alpha chain; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pat [...] | 0.749 |
HP | A0A287ALX3_PIG | ENSSSCP00000043076 | ENSSSCP00000044902 | Haptoglobin alpha chain; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pat [...] | Uncharacterized protein. | 0.506 |