node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALYREF | SNRPE | ENSSSCP00000071154 | ENSSSCP00000022254 | Aly/REF export factor. | Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. | 0.754 |
ALYREF | SNRPF | ENSSSCP00000071154 | ENSSSCP00000000958 | Aly/REF export factor. | Sm domain-containing protein. | 0.784 |
ALYREF | SNRPG | ENSSSCP00000071154 | ENSSSCP00000025138 | Aly/REF export factor. | Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. | 0.732 |
ALYREF | TRNAU1AP | ENSSSCP00000071154 | ENSSSCP00000046008 | Aly/REF export factor. | tRNA selenocysteine 1-associated protein 1. | 0.674 |
ALYREF | U2AF2 | ENSSSCP00000071154 | ENSSSCP00000042718 | Aly/REF export factor. | U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family. | 0.814 |
PRPF39 | RBM25 | ENSSSCP00000005374 | ENSSSCP00000058947 | Pre-mRNA processing factor 39. | RNA binding motif protein 25. | 0.898 |
PRPF39 | SF3B1 | ENSSSCP00000005374 | ENSSSCP00000031130 | Pre-mRNA processing factor 39. | Splicing factor 3B subunit 1 isoform 1. | 0.964 |
PRPF39 | SNRPA1 | ENSSSCP00000005374 | ENSSSCP00000064487 | Pre-mRNA processing factor 39. | Small nuclear ribonucleoprotein polypeptide A. | 0.884 |
PRPF39 | SNRPD1 | ENSSSCP00000005374 | ENSSSCP00000004008 | Pre-mRNA processing factor 39. | Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. | 0.891 |
PRPF39 | SNRPE | ENSSSCP00000005374 | ENSSSCP00000022254 | Pre-mRNA processing factor 39. | Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. | 0.781 |
PRPF39 | SNRPF | ENSSSCP00000005374 | ENSSSCP00000000958 | Pre-mRNA processing factor 39. | Sm domain-containing protein. | 0.889 |
PRPF39 | SNRPG | ENSSSCP00000005374 | ENSSSCP00000025138 | Pre-mRNA processing factor 39. | Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. | 0.802 |
PRPF39 | TRNAU1AP | ENSSSCP00000005374 | ENSSSCP00000046008 | Pre-mRNA processing factor 39. | tRNA selenocysteine 1-associated protein 1. | 0.847 |
PRPF39 | U2AF2 | ENSSSCP00000005374 | ENSSSCP00000042718 | Pre-mRNA processing factor 39. | U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family. | 0.771 |
RBM25 | PRPF39 | ENSSSCP00000058947 | ENSSSCP00000005374 | RNA binding motif protein 25. | Pre-mRNA processing factor 39. | 0.898 |
RBM25 | SF3B1 | ENSSSCP00000058947 | ENSSSCP00000031130 | RNA binding motif protein 25. | Splicing factor 3B subunit 1 isoform 1. | 0.872 |
RBM25 | SNRPA1 | ENSSSCP00000058947 | ENSSSCP00000064487 | RNA binding motif protein 25. | Small nuclear ribonucleoprotein polypeptide A. | 0.974 |
RBM25 | SNRPD1 | ENSSSCP00000058947 | ENSSSCP00000004008 | RNA binding motif protein 25. | Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. | 0.843 |
RBM25 | SNRPE | ENSSSCP00000058947 | ENSSSCP00000022254 | RNA binding motif protein 25. | Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. | 0.672 |
RBM25 | SNRPF | ENSSSCP00000058947 | ENSSSCP00000000958 | RNA binding motif protein 25. | Sm domain-containing protein. | 0.851 |