STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMC8Transmembrane channel-like protein. (699 aa)    
Predicted Functional Partners:
KCNG4
Potassium voltage-gated channel modifier subfamily G member 4; Belongs to the potassium channel family.
    
 
 0.829
SYNGR2
Synaptogyrin.
 
    
 0.829
CPT2
Carn_acyltransf domain-containing protein; Belongs to the carnitine/choline acetyltransferase family.
    
 
 0.672
MYBPC1
Myosin binding protein C, slow type.
    
 
 0.618
WDR18
WD repeat-containing protein 18.
   
 
 0.571
SASH3
SAM and SH3 domain containing 3.
   
 
 0.566
SH2D3A
SH2 domain containing 3A.
   
 
 0.530
DCAF6
DDB1-and CUL4-associated factor 6 isoform c.
      
 0.529
CCDC102A
Coiled-coil domain containing 102A.
      
 0.513
BIRC5
Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...]
    
 
 0.508
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.