STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDKL5Cyclin dependent kinase like 5. (999 aa)    
Predicted Functional Partners:
PRUNE1
Prune exopolyphosphatase 1.
      
 0.760
MECP2
Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).
    
 
 0.636
BLOC1S4
Biogenesis of lysosomal organelles complex 1 subunit 4.
      
 0.575
CD99L2
CD99 molecule like 2.
   
  
 0.569
TTLL4
Tubulin tyrosine ligase like 4.
      
 0.566
FOXG1
Forkhead box G1.
      
 0.563
UTP11
U3 small nucleolar RNA-associated protein 11; Involved in nucleolar processing of pre-18S ribosomal RNA.
      
 0.555
KCTD18
BTB/POZ domain-containing protein KCTD18 isoform 1.
      
 0.555
FAM234A
Family with sequence similarity 234 member A.
      
 0.555
KIAA1217
KIAA1217.
      
 0.555
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.