STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLEKHB1Pleckstrin homology domain containing B1. (292 aa)    
Predicted Functional Partners:
SYNGR4
Synaptogyrin.
      
 0.844
WDR25
WD repeat domain 25.
      
 0.729
TEX26
Testis expressed 26.
      
 0.695
CCKBR
Gastrin/cholecystokinin type B receptor; Receptor for gastrin and cholecystokinin. The CCK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity (Probable). This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (Probable); Belongs to the G-protein coupled receptor 1 family.
      
 0.691
DENND4A
DENN domain containing 4A.
      
 0.673
KIAA0408
KIAA0408.
      
 0.609
CAMTA1
Calmodulin binding transcription activator 1.
      
 0.601
MXD3
MAX dimerization protein 3.
      
 0.588
PLEKHH1
Pleckstrin homology, MyTH4 and FERM domain containing H1.
      
 0.560
CLCA4
Chloride channel accessory 4.
    
 
 0.546
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.