STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDH12Cadherin-12 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. (794 aa)    
Predicted Functional Partners:
CRACD
KIAA1211.
    
 
 0.710
CDH8
Cadherin 8; Cadherins are calcium-dependent cell adhesion proteins.
    
0.677
GAS8
Growth arrest specific 8.
      
 0.672
CTNNB1
Catenin beta 1.
    
 0.665
CDH24
Cadherin-24 isoform 2; Cadherins are calcium-dependent cell adhesion proteins.
  
 
 
0.655
CDH7
Cadherin-7 isoform 1 preproprotein; Cadherins are calcium-dependent cell adhesion proteins.
  
 
0.633
JUP
Junction plakoglobin; Common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE- cadherin function in endothelial cells. Can replace beta-catenin in E- cadherin/catenin adhes [...]
    
 0.630
CDH2
Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins.
  
 
0.623
RNF157
Ring finger protein 157.
      
 0.622
CTNND1
Catenin delta 1.
    
 0.617
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.