STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A287AUC1_PIGEF-hand domain-containing protein; Belongs to the calmodulin family. (87 aa)    
Predicted Functional Partners:
MIP
Major intrinsic protein of lens fiber; Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
 
 0.723
FKBP1A
Peptidylprolyl isomerase.
   
 
 0.702
CAMK2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha isoform 1; Belongs to the protein kinase superfamily.
   
 
 0.663
TRPV1
Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family.
    
 
 0.645
IQGAP1
IQ motif containing GTPase activating protein 1.
    
 
 0.637
CAMK2B
Calcium/calmodulin dependent protein kinase II beta.
   
 
 0.609
CAMK2D
Calcium/calmodulin-dependent protein kinase type II subunit delta; Calcium/calmodulin-dependent protein kinase involved in the regulation of Ca(2+) homeostatis and excitation-contraction coupling (ECC) in heart by targeting ion channels, transporters and accessory proteins involved in Ca(2+) influx into the myocyte, Ca(2+) release from the sarcoplasmic reticulum (SR), SR Ca(2+) uptake and Na(+) and K(+) channel transport. Targets also transcription factors and signaling molecules to regulate heart function. In its activated form, is involved in the pathogenesis of dilated cardiomyopath [...]
   
 
 0.609
ASPM
Abnormal spindle microtubule assembly.
    
 
 0.603
CNN2
Calponin-2; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.
   
 
 0.602
TRPV5
Transient receptor potential cation channel subfamily V member 5; Belongs to the transient receptor (TC 1.A.4) family.
    
 
 0.564
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.