NGEF protein (Sus scrofa) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

NGEF

Neuronal guanine nucleotide exchange factor. (823 aa)

Predicted Functional Partners:

EPHA4

0.950

EPHA1

0.937

RHOA

0.928

CDC42

0.924

EPHA2

0.918

EPHB2

0.915

RAC3

0.914

EPHB1

0.912

EPHA5

0.911

EPHA3

0.911

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC42	EPHA2	ENSSSCP00000029815	ENSSSCP00000003769	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	Ephrin type-A receptor 2 isoform 1.	0.549
CDC42	NGEF	ENSSSCP00000029815	ENSSSCP00000047695	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	Neuronal guanine nucleotide exchange factor.	0.924
CDC42	RAC3	ENSSSCP00000029815	ENSSSCP00000047362	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	Rac family small GTPase 3.	0.929
CDC42	RHOA	ENSSSCP00000029815	ENSSSCP00000045785	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	Transforming protein RhoA isoform 1.	0.948
EPHA1	EPHA2	ENSSSCP00000017441	ENSSSCP00000003769	Ephrin type-A receptor 1.	Ephrin type-A receptor 2 isoform 1.	0.810
EPHA1	EPHA3	ENSSSCP00000017441	ENSSSCP00000023658	Ephrin type-A receptor 1.	Ephrin type-A receptor 3 isoform X1.	0.605
EPHA1	EPHA4	ENSSSCP00000017441	ENSSSCP00000017193	Ephrin type-A receptor 1.	EPH receptor A4.	0.604
EPHA1	EPHA5	ENSSSCP00000017441	ENSSSCP00000009514	Ephrin type-A receptor 1.	EPH receptor A5.	0.587
EPHA1	EPHB1	ENSSSCP00000017441	ENSSSCP00000022406	Ephrin type-A receptor 1.	Ephrin type-B receptor 1.	0.674
EPHA1	EPHB2	ENSSSCP00000017441	ENSSSCP00000003828	Ephrin type-A receptor 1.	EPH receptor B2.	0.653
EPHA1	NGEF	ENSSSCP00000017441	ENSSSCP00000047695	Ephrin type-A receptor 1.	Neuronal guanine nucleotide exchange factor.	0.937
EPHA2	CDC42	ENSSSCP00000003769	ENSSSCP00000029815	Ephrin type-A receptor 2 isoform 1.	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	0.549
EPHA2	EPHA1	ENSSSCP00000003769	ENSSSCP00000017441	Ephrin type-A receptor 2 isoform 1.	Ephrin type-A receptor 1.	0.810
EPHA2	EPHA3	ENSSSCP00000003769	ENSSSCP00000023658	Ephrin type-A receptor 2 isoform 1.	Ephrin type-A receptor 3 isoform X1.	0.534
EPHA2	EPHA4	ENSSSCP00000003769	ENSSSCP00000017193	Ephrin type-A receptor 2 isoform 1.	EPH receptor A4.	0.620
EPHA2	EPHA5	ENSSSCP00000003769	ENSSSCP00000009514	Ephrin type-A receptor 2 isoform 1.	EPH receptor A5.	0.595
EPHA2	EPHB1	ENSSSCP00000003769	ENSSSCP00000022406	Ephrin type-A receptor 2 isoform 1.	Ephrin type-B receptor 1.	0.706
EPHA2	EPHB2	ENSSSCP00000003769	ENSSSCP00000003828	Ephrin type-A receptor 2 isoform 1.	EPH receptor B2.	0.703
EPHA2	NGEF	ENSSSCP00000003769	ENSSSCP00000047695	Ephrin type-A receptor 2 isoform 1.	Neuronal guanine nucleotide exchange factor.	0.918
EPHA2	RAC3	ENSSSCP00000003769	ENSSSCP00000047362	Ephrin type-A receptor 2 isoform 1.	Rac family small GTPase 3.	0.571