STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SYT7Synaptotagmin-7 isoform X2. (686 aa)    
Predicted Functional Partners:
RAB3A
Ras-related protein Rab-3A; Small GTP-binding protein that plays a central role in regulated exocytosis and secretion. Controls the recruitment, tethering and docking of secretory vesicles to the plasma membrane (By similarity). Upon stimulation, switches to its active GTP-bound form, cycles to vesicles and recruits effectors such as RIMS1, RIMS2, Rabphilin-3A/RPH3A, RPH3AL or SYTL4 to help the docking of vesicules onto the plasma membrane (By similarity). Upon GTP hydrolysis by GTPase-activating protein, dissociates from the vesicle membrane allowing the exocytosis to proceed (By simi [...]
   
 
 0.641
NSF
N-ethylmaleimide sensitive factor, vesicle fusing ATPase.
   
 
 0.579
SNAP25
Synaptosomal-associated protein; Belongs to the SNAP-25 family.
   
 
 0.570
SYN2
Synapsin II.
    
 
 0.569
STX1A
Syntaxin 1A; Belongs to the syntaxin family.
    
 
 0.556
VAMP2
V-SNARE coiled-coil homology domain-containing protein.
   
 
 0.554
CHGB
Secretogranin-1; Secretogranin-1 is a neuroendocrine secretory granule protein, which may be the precursor for other biologically active peptides.
   
 
 0.544
ATP8B4
Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
      
 0.531
SNAP23
Synaptosomal-associated protein; Belongs to the SNAP-25 family.
   
 
 0.530
GAL3ST4
Galactose-3-O-sulfotransferase 4.
      
 0.503
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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