STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GFRA1GDNF family receptor alpha 1. (570 aa)    
Predicted Functional Partners:
GDNF
Glial cell line-derived neurotrophic factor isoform 1.
    
 0.988
RET
Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.
    
 0.983
NRTN
Neurturin.
    
 0.863
ZBTB16
Zinc finger and BTB domain containing 16.
      
 0.760
PSPN
Persephin.
     
 0.730
STRA8
Stimulated by retinoic acid 8.
      
 0.716
ETV5
ETS variant 5.
      
 0.690
DAZL
Deleted in azoospermia-like protein.
      
 0.690
BCL6B
BCL6B transcription repressor.
      
 0.658
SOHLH1
BHLH domain-containing protein.
      
 0.645
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.