STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SERPINF1Serpin family F member 1; Belongs to the serpin family. (433 aa)    
Predicted Functional Partners:
LRP5
Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.
    
 0.920
LRP6
Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.
    
 0.918
CRTAP
Cartilage-associated protein.
      
 0.653
FMOD
Fibromodulin; Affects the rate of fibrils formation. May have a primary role in collagen fibrillogenesis (By similarity).
   
  
 0.616
FKBP10
Peptidylprolyl isomerase.
   
 
 0.580
BEST1
Bestrophin-1; Forms calcium-sensitive chloride channels. Permeable to bicarbonate (By similarity); Belongs to the bestrophin family.
      
 0.567
RPE65
Retinoid isomerohydrolase RPE65.
   
  
 0.562
TMEM38B
Trimeric intracellular cation channel type B.
      
 0.558
CLEC3B
C-type lectin domain family 3 member B.
   
  
 0.518
ECRG4
ECRG4 augurin precursor.
      
 0.516
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.