CPS1 protein (Sus scrofa) - STRING interaction network

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Known Interactions

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Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

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[Homology]

Score

CPS1

Carbamoyl-phosphate synthase 1. (1425 aa)

Predicted Functional Partners:

OTC

0.997

ASS1

0.995

GLUD1

0.974

GLUL

0.965

NAGS

0.923

ASL

0.919

GLS2

0.917

GLS

0.907

CAD

0.903

DHODH

0.794

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASL	ASS1	ENSSSCP00000008264	ENSSSCP00000040581	Argininosuccinate lyase isoform 1.	Argininosuccinate synthase 1.	0.999
ASL	CAD	ENSSSCP00000008264	ENSSSCP00000025052	Argininosuccinate lyase isoform 1.	Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase.	0.723
ASL	CPS1	ENSSSCP00000008264	ENSSSCP00000051055	Argininosuccinate lyase isoform 1.	Carbamoyl-phosphate synthase 1.	0.919
ASL	GLUD1	ENSSSCP00000008264	ENSSSCP00000011056	Argininosuccinate lyase isoform 1.	Glutamate dehydrogenase 1, mitochondrial; Mitochondrial glutamate dehydrogenase that converts L- glutamate into alpha-ketoglutarate. Plays a key role in glutamine anaplerosis by producing alpha-ketoglutarate, an important intermediate in the tricarboxylic acid cycle. May be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate (By similarity).	0.566
ASL	GLUL	ENSSSCP00000008264	ENSSSCP00000042620	Argininosuccinate lyase isoform 1.	Glutamine synthetase; Glutamine synthetase that catalyzes the ATP-dependent conversion of glutamate and ammonia to glutamine (By similarity). Its role depends on tissue localization: in the brain, it regulates the levels of toxic ammonia and converts neurotoxic glutamate to harmless glutamine, whereas in the liver, it is one of the enzymes responsible for the removal of ammonia (By similarity). Essential for proliferation of fetal skin fibroblasts. Independently of its glutamine synthetase activity, required for endothelial cell migration during vascular development: acts by regulating [...]	0.556
ASL	NAGS	ENSSSCP00000008264	ENSSSCP00000025512	Argininosuccinate lyase isoform 1.	N-acetyltransferase domain-containing protein.	0.997
ASL	OTC	ENSSSCP00000008264	ENSSSCP00000072423	Argininosuccinate lyase isoform 1.	Ornithine carbamoyltransferase, mitochondrial; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.	0.982
ASS1	ASL	ENSSSCP00000040581	ENSSSCP00000008264	Argininosuccinate synthase 1.	Argininosuccinate lyase isoform 1.	0.999
ASS1	CAD	ENSSSCP00000040581	ENSSSCP00000025052	Argininosuccinate synthase 1.	Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase.	0.988
ASS1	CPS1	ENSSSCP00000040581	ENSSSCP00000051055	Argininosuccinate synthase 1.	Carbamoyl-phosphate synthase 1.	0.995
ASS1	GLS	ENSSSCP00000040581	ENSSSCP00000055263	Argininosuccinate synthase 1.	Glutaminase.	0.406
ASS1	GLS2	ENSSSCP00000040581	ENSSSCP00000000427	Argininosuccinate synthase 1.	Glutaminase 2.	0.643
ASS1	GLUD1	ENSSSCP00000040581	ENSSSCP00000011056	Argininosuccinate synthase 1.	Glutamate dehydrogenase 1, mitochondrial; Mitochondrial glutamate dehydrogenase that converts L- glutamate into alpha-ketoglutarate. Plays a key role in glutamine anaplerosis by producing alpha-ketoglutarate, an important intermediate in the tricarboxylic acid cycle. May be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate (By similarity).	0.500
ASS1	GLUL	ENSSSCP00000040581	ENSSSCP00000042620	Argininosuccinate synthase 1.	Glutamine synthetase; Glutamine synthetase that catalyzes the ATP-dependent conversion of glutamate and ammonia to glutamine (By similarity). Its role depends on tissue localization: in the brain, it regulates the levels of toxic ammonia and converts neurotoxic glutamate to harmless glutamine, whereas in the liver, it is one of the enzymes responsible for the removal of ammonia (By similarity). Essential for proliferation of fetal skin fibroblasts. Independently of its glutamine synthetase activity, required for endothelial cell migration during vascular development: acts by regulating [...]	0.477
ASS1	NAGS	ENSSSCP00000040581	ENSSSCP00000025512	Argininosuccinate synthase 1.	N-acetyltransferase domain-containing protein.	0.977
ASS1	OTC	ENSSSCP00000040581	ENSSSCP00000072423	Argininosuccinate synthase 1.	Ornithine carbamoyltransferase, mitochondrial; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.	0.999
CAD	ASL	ENSSSCP00000025052	ENSSSCP00000008264	Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase.	Argininosuccinate lyase isoform 1.	0.723
CAD	ASS1	ENSSSCP00000025052	ENSSSCP00000040581	Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase.	Argininosuccinate synthase 1.	0.988
CAD	CPS1	ENSSSCP00000025052	ENSSSCP00000051055	Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase.	Carbamoyl-phosphate synthase 1.	0.903
CAD	DHODH	ENSSSCP00000025052	ENSSSCP00000066486	Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase.	Dihydroorotate dehydrogenase (quinone).	0.987