node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
APP | CTRB2 | ENSSSCP00000012805 | ENSSSCP00000024109 | Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...] | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. | 0.401 |
APP | CTRL | ENSSSCP00000012805 | ENSSSCP00000021733 | Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...] | Chymotrypsin like; Belongs to the peptidase S1 family. | 0.402 |
APP | LOC100621820 | ENSSSCP00000012805 | ENSSSCP00000023533 | Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...] | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. | 0.838 |
APP | LOC100739735 | ENSSSCP00000012805 | ENSSSCP00000051113 | Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...] | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. | 0.838 |
APP | PRSS2 | ENSSSCP00000012805 | ENSSSCP00000017461 | Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...] | Putative trypsinogen; Belongs to the peptidase S1 family. | 0.840 |
CEL | CTRL | ENSSSCP00000027456 | ENSSSCP00000021733 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | Chymotrypsin like; Belongs to the peptidase S1 family. | 0.904 |
CEL | LOC100621820 | ENSSSCP00000027456 | ENSSSCP00000023533 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. | 0.824 |
CEL | LOC100739735 | ENSSSCP00000027456 | ENSSSCP00000051113 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. | 0.847 |
CEL | LOC110261434 | ENSSSCP00000027456 | ENSSSCP00000054486 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. | 0.945 |
CEL | PNLIP | ENSSSCP00000027456 | ENSSSCP00000011355 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | Pancreatic triacylglycerol lipase. | 0.987 |
CEL | PNLIPRP1 | ENSSSCP00000027456 | ENSSSCP00000011357 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. | 0.986 |
CEL | PNLIPRP2 | ENSSSCP00000027456 | ENSSSCP00000050863 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. | 0.987 |
CTRB2 | APP | ENSSSCP00000024109 | ENSSSCP00000012805 | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. | Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...] | 0.401 |
CTRB2 | LOC100621820 | ENSSSCP00000024109 | ENSSSCP00000023533 | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. | 0.902 |
CTRB2 | LOC100739735 | ENSSSCP00000024109 | ENSSSCP00000051113 | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. | 0.903 |
CTRB2 | PNLIP | ENSSSCP00000024109 | ENSSSCP00000011355 | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. | Pancreatic triacylglycerol lipase. | 0.788 |
CTRB2 | PNLIPRP1 | ENSSSCP00000024109 | ENSSSCP00000011357 | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. | Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. | 0.787 |
CTRB2 | PNLIPRP2 | ENSSSCP00000024109 | ENSSSCP00000050863 | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. | Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. | 0.787 |
CTRB2 | PRSS2 | ENSSSCP00000024109 | ENSSSCP00000017461 | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. | Putative trypsinogen; Belongs to the peptidase S1 family. | 0.655 |
CTRL | APP | ENSSSCP00000021733 | ENSSSCP00000012805 | Chymotrypsin like; Belongs to the peptidase S1 family. | Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...] | 0.402 |